Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. However, HD patients have markedly increased rates of cardiovascular morbidity and mortality. Previously, a link between the complement system and cardiovascular events (CV-events) has been reported. In HD, systemic complement activation occurs due to blood-to-membrane interaction. We hypothesize that HD-induced complement activation together with inflammation and thrombosis are involved in the development of CV-events in these patients. Methods: HD patients were followed for the occurrence of CV-events during a maximum follow-up of 45 months. Plasma samples were collected from 55 patients at different time points during one HD session prior ...
Deregulation or excessive activation of the complement system is now considered a fundamental aspect...
Fluid phase generation of terminal complement complex as a novel index of bioincompatibility. Blood ...
Abstract Background The complement system is vital for innate immunity and is implicated in the path...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Individuals receiving long-term hemodialysis are at increased risk of developing cardiovascular dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
<b><i>Background:</i></b> Patients on haemodialysis (HD) have high rates of cardiovascular (CV) dise...
Complement components as uremic toxins and their potential role as mediators of microinflammation. C...
Chronic kidney disease (CKD) is a growing health problem with a prevalence of approximately 10-15% w...
Thrombosis is a common complication of end-stage renal disease, particularly in patients on hemodial...
The role of the complement system in the induction of cytokine release is controversial. Plasma term...
Significant advances have lead to a greater understanding of the role of the complement system withi...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Deregulation or excessive activation of the complement system is now considered a fundamental aspect...
Fluid phase generation of terminal complement complex as a novel index of bioincompatibility. Blood ...
Abstract Background The complement system is vital for innate immunity and is implicated in the path...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Individuals receiving long-term hemodialysis are at increased risk of developing cardiovascular dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
<b><i>Background:</i></b> Patients on haemodialysis (HD) have high rates of cardiovascular (CV) dise...
Complement components as uremic toxins and their potential role as mediators of microinflammation. C...
Chronic kidney disease (CKD) is a growing health problem with a prevalence of approximately 10-15% w...
Thrombosis is a common complication of end-stage renal disease, particularly in patients on hemodial...
The role of the complement system in the induction of cytokine release is controversial. Plasma term...
Significant advances have lead to a greater understanding of the role of the complement system withi...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Deregulation or excessive activation of the complement system is now considered a fundamental aspect...
Fluid phase generation of terminal complement complex as a novel index of bioincompatibility. Blood ...
Abstract Background The complement system is vital for innate immunity and is implicated in the path...