The pathophysiology of aortic aneurysms (AA) is far from being understood. One reason for this lack of understanding is basic research being constrained to fixated cells or isolated cell cultures, by which cell-to-cell and cell-to-matrix communications are missed. We present a new, in vitro method for extended preservation of aortic wall sections to study pathophysiological processes. Intraoperatively harvested, live aortic specimens were cut into 150 μm sections and cultured. Viability was quantified up to 92 days using immunofluorescence. Cell types were characterized using immunostaining. After 14 days, individual cells of enzymatically digested tissues were examined for cell type and viability. Analysis of AA sections (N = 8) showed a v...
PurposeAbdominal aortic aneurysms (AAAs) expand because of aortic wall destruction. Enrichment in Va...
Abdominal aortic aneurysm (AAA) is an asymptomatic dilatation of the abdominal aorta which ultimatel...
TITLE: Role of bone marrow mesenchymal stem cells in the stabilization of elastase- induced ascendin...
The pathophysiology of aortic aneurysms (AA) is far from being understood. One reason for this lack ...
Aortic diseases are diverse and involve a multiplicity of biological systems in the vascular wall. A...
AbstractPurpose: Abdominal aortic aneurysms are characterized by degradation of the extracellular ma...
Ruptured abdominal aortic aneurysms (AAA) are associated with overall mortality rates up to 90%. Des...
INTRODUCTION: Abdominal aortic aneurysms (AAAs) are associated with overall high mortality in case o...
<p>(<b>A</b>) The various steps of the isolation protocol are displayed. (<b>B</b>) A representative...
Objective: In cardiovascular tissue engineering, three-dimensional scaffolds serve as physical suppo...
ObjectiveAbdominal aortic aneurysm (AAA) progression and disease resistance are related to mural cel...
Yes(1) Abdominal aortic aneurysm (AAA) is a silent, progressive disease with significant mortality f...
Abstract An aortic aneurysm (AA) is defined as focal aortic dilation that occurs mainly with older a...
An abdominal aortic aneurysm (AAA) is a localized expansion of the aorta. This disease can sometimes...
An abdominal aortic aneurysm (AAA) is a localized expansion of the aorta. This disease can sometimes...
PurposeAbdominal aortic aneurysms (AAAs) expand because of aortic wall destruction. Enrichment in Va...
Abdominal aortic aneurysm (AAA) is an asymptomatic dilatation of the abdominal aorta which ultimatel...
TITLE: Role of bone marrow mesenchymal stem cells in the stabilization of elastase- induced ascendin...
The pathophysiology of aortic aneurysms (AA) is far from being understood. One reason for this lack ...
Aortic diseases are diverse and involve a multiplicity of biological systems in the vascular wall. A...
AbstractPurpose: Abdominal aortic aneurysms are characterized by degradation of the extracellular ma...
Ruptured abdominal aortic aneurysms (AAA) are associated with overall mortality rates up to 90%. Des...
INTRODUCTION: Abdominal aortic aneurysms (AAAs) are associated with overall high mortality in case o...
<p>(<b>A</b>) The various steps of the isolation protocol are displayed. (<b>B</b>) A representative...
Objective: In cardiovascular tissue engineering, three-dimensional scaffolds serve as physical suppo...
ObjectiveAbdominal aortic aneurysm (AAA) progression and disease resistance are related to mural cel...
Yes(1) Abdominal aortic aneurysm (AAA) is a silent, progressive disease with significant mortality f...
Abstract An aortic aneurysm (AA) is defined as focal aortic dilation that occurs mainly with older a...
An abdominal aortic aneurysm (AAA) is a localized expansion of the aorta. This disease can sometimes...
An abdominal aortic aneurysm (AAA) is a localized expansion of the aorta. This disease can sometimes...
PurposeAbdominal aortic aneurysms (AAAs) expand because of aortic wall destruction. Enrichment in Va...
Abdominal aortic aneurysm (AAA) is an asymptomatic dilatation of the abdominal aorta which ultimatel...
TITLE: Role of bone marrow mesenchymal stem cells in the stabilization of elastase- induced ascendin...