Effect of early nutritional intake on long-term growth and bone mineralization of former very low birth weight infants

Christmann, V.
van der Putten, M. E.
Rodwell, L.
Steiner, K.
Gotthardt, M.
van Goudoever, J. B.
van Heijst, A. F. J.

Open link

Publication date

January 2018

DOI

10.1016/j.bone.2017.12.022

Publisher

Elsevier BV

Abstract

Preterm infants are at risk for impaired bone mineralization and growth in length later in life due to inadequate nutritional intake in the early postnatal period. To investigate whether increased nutritional supplementation of calcium, phosphate and protein in Very Low Birth Weight (VLBW) infants during the first 14days after birth was associated with improvement in length and bone development until 9-10years of age. Observational follow-up study of VLBW infants (birth weight <1500g or gestational age <32weeks) born in two consecutive years (eligible infants: 2004 n: 63 and 2005: n: 66). Cohort 2005 received higher intake of calcium, phosphate and protein with parenteral nutrition compared to Cohort 2004. Anthropometric data were collected...