Infection with oncogenic human papillomavirus (HPV) types is associated with the development of cervical neoplasia (CIN). The E6 and E7 oncoproteins are constitutively expressed in these lesions and are therefore putative targets for the immune response against HPV. The relation between HPV 16-specific memory cytotoxic T-cell precursor (mCTLp) activity to both oncoproteins and the natural course of cervical dysplasia was analyzed in 38 patients participating in a nonintervention cohort study of women with CIN and II HPV 16-positive cervical carcinoma patients. In a cross-sectional study at the end of follow-up prior to biopsy, 8 of 20 patients with a persistent HPV 16 infection had specific mCTLp against at least one of the two oncoproteins...
Human papillomavirus (HPV) infection, especially with the oncogenic genotypes, is the most important...
Aims-To investigate the correlation between antibodies to the transforming protein E7 of human papil...
Human papillomavirus (HPV) infection, particularly type 16, is causally associated with the developm...
Human papillomaviruses (HPVs), especially types 16 and 18, are strongly associated with the developm...
T-cell-mediated immune responses against oncogenic human papillomaviruses (HPVs) are believed to pla...
T cell proliferative responses against human papillomavirus type 16 (HPV-16) E7 protein were studied...
type 16 (HPV16) is a major cause of high-grade cervical intraepithelial neoplasia (CIN). Experiments...
Cervical cancer is the possible outcome of genital infection with high-risk human papillomavirus (HP...
It is presently the right time for clarifying human papillomavirus (HPV)- associated cellular immuni...
T-cell-mediated immune responses against mucosal oncogenic types of human papillomaviruses (HPV) are...
Cervical neoplastic lesions are associated with infection by high-risk human papilloma-viruses (HPV)...
The cellular tumor suppressor p16 is strongly overexpressed in cervical cancers and precancers. We h...
Previously, we found that human papillomavirus type 16 (HPV- 16) E5 protein is a tumor rejection ant...
Persistent human papillomavirus type 16 (HPV16) infection is associated with the development of more...
Human papillomavirus (HPV) infection, particularly type 16, is causally associated with the developm...
Human papillomavirus (HPV) infection, especially with the oncogenic genotypes, is the most important...
Aims-To investigate the correlation between antibodies to the transforming protein E7 of human papil...
Human papillomavirus (HPV) infection, particularly type 16, is causally associated with the developm...
Human papillomaviruses (HPVs), especially types 16 and 18, are strongly associated with the developm...
T-cell-mediated immune responses against oncogenic human papillomaviruses (HPVs) are believed to pla...
T cell proliferative responses against human papillomavirus type 16 (HPV-16) E7 protein were studied...
type 16 (HPV16) is a major cause of high-grade cervical intraepithelial neoplasia (CIN). Experiments...
Cervical cancer is the possible outcome of genital infection with high-risk human papillomavirus (HP...
It is presently the right time for clarifying human papillomavirus (HPV)- associated cellular immuni...
T-cell-mediated immune responses against mucosal oncogenic types of human papillomaviruses (HPV) are...
Cervical neoplastic lesions are associated with infection by high-risk human papilloma-viruses (HPV)...
The cellular tumor suppressor p16 is strongly overexpressed in cervical cancers and precancers. We h...
Previously, we found that human papillomavirus type 16 (HPV- 16) E5 protein is a tumor rejection ant...
Persistent human papillomavirus type 16 (HPV16) infection is associated with the development of more...
Human papillomavirus (HPV) infection, particularly type 16, is causally associated with the developm...
Human papillomavirus (HPV) infection, especially with the oncogenic genotypes, is the most important...
Aims-To investigate the correlation between antibodies to the transforming protein E7 of human papil...
Human papillomavirus (HPV) infection, particularly type 16, is causally associated with the developm...