Priming with a dopamine agonist greatly enhances the behavioral effectiveness of dopamine D1 receptor agonists in rats with 6-hydroxydopamine lesions of the nigrostriatal pathway. The present study investigated the influence of priming on cyclic AMP production in striatal slices. Stimulation of dopamine D1 receptors with dopamine or the dopamine D1 receptor agonist, 1-phenyl-6-Cl-7,8-diol-2,3,4,5-tetrahydro-(1H)-3-benzazepine (SKF 81297), increased cyclic AMP production in the lesioned striatum of rats primed with L-3,4-dihydroxyphenylalanine (L-DOPA) by 329% and 405%, respectively, whereas in drug-naive rats the increase was 183% and 187%, respectively. Priming with quinpirole produced similar results. It is suggested that priming with eit...
The D1 agonist, SKF 38393, failed to induce contralateral turning in drug-naive rats lesioned unilat...
To examine the role of Dl dopamine receptors in modulating basal ganglia output and how this role ma...
In rats bearing unilateral 6-hydroxydopamine (6-OHDA) lesions of the dopaminergic nigro-striatal neu...
Priming with a dopamine agonist greatly enhances the behavioral effectiveness of dopamine D1 recepto...
''Priming'' is a phenomenon of behavioural sensitization observed in unilaterally 6-hydroxy-dopamine...
''Priming'' is a phenomenon of behavioural sensitization observed in unilaterally 6-hydroxy-dopamine...
A single dose of the D-1 agonist SKF 38393 (3mg/kg) produces contralateral turning in unilaterally 6...
The D-1 agonist SKF 38393 (2 mg/kg s.c.) failed to induce contralateral turning in drug-naive rats, ...
he D1 agonist, SKF 38393, failed to induce contralateral turning in drug-naive rats lesioned unilate...
Previous single exposure (priming) to a dopamine receptor agonist greatly enhances the contralateral...
The present study investigated long-term alterations in striatal gene expression after single exposu...
The effects of MK-801, a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist, of quinpir...
Receptor priming is a recently discovered phenomenon by which receptor agonists produce abrupt and l...
A previous study of our group demonstrated that movement performance induced by dopamine agonist dru...
In rats bearing a unilateral 6-hydroxydopamine (6-OHDA) lesion of the medial forebrain bundle, a sin...
The D1 agonist, SKF 38393, failed to induce contralateral turning in drug-naive rats lesioned unilat...
To examine the role of Dl dopamine receptors in modulating basal ganglia output and how this role ma...
In rats bearing unilateral 6-hydroxydopamine (6-OHDA) lesions of the dopaminergic nigro-striatal neu...
Priming with a dopamine agonist greatly enhances the behavioral effectiveness of dopamine D1 recepto...
''Priming'' is a phenomenon of behavioural sensitization observed in unilaterally 6-hydroxy-dopamine...
''Priming'' is a phenomenon of behavioural sensitization observed in unilaterally 6-hydroxy-dopamine...
A single dose of the D-1 agonist SKF 38393 (3mg/kg) produces contralateral turning in unilaterally 6...
The D-1 agonist SKF 38393 (2 mg/kg s.c.) failed to induce contralateral turning in drug-naive rats, ...
he D1 agonist, SKF 38393, failed to induce contralateral turning in drug-naive rats lesioned unilate...
Previous single exposure (priming) to a dopamine receptor agonist greatly enhances the contralateral...
The present study investigated long-term alterations in striatal gene expression after single exposu...
The effects of MK-801, a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist, of quinpir...
Receptor priming is a recently discovered phenomenon by which receptor agonists produce abrupt and l...
A previous study of our group demonstrated that movement performance induced by dopamine agonist dru...
In rats bearing a unilateral 6-hydroxydopamine (6-OHDA) lesion of the medial forebrain bundle, a sin...
The D1 agonist, SKF 38393, failed to induce contralateral turning in drug-naive rats lesioned unilat...
To examine the role of Dl dopamine receptors in modulating basal ganglia output and how this role ma...
In rats bearing unilateral 6-hydroxydopamine (6-OHDA) lesions of the dopaminergic nigro-striatal neu...