Add to ORKGWhat is already known about this topic? Approximately 2.9 million cholera cases occur each year worldwide, and 1.3 billion persons are at risk for infection, usually from contaminated drinking water. What is added by this report? A cholera outbreak that began in October 2017 in Zambia has resulted in approximately 5,900 cases and 114 deaths. The government improved the water supply and administered oral cholera vaccine, but flooding led to a resurgence of cholera. A multisectoral and well-coordinated response was key to the control of the outbreak. What are the implications for public health practice? Gains can be made in outbreak control with a robust public health response. However, cholera resurgence remains a risk unless access to safe ...