Toxoplasmosis is a highly prolific and neglected disease, and current treatments fail to adequately address the challenges it presents. As such development of new more efficacious treatments, tailored to the complex nature of the infection, is required. The causative parasite Toxoplasma gondii is a resilient and resourceful organism, adept at invasion, avoidance and survival within its host. The cytochrome bc1 complex has been proven to be a validated target for the treatment of a number of apicomplexan parasitic diseases, including both malaria and toxoplasmosis. Recent work has also identified overexpression of this complex within a strain expressing the difficult to treat bradyzoite phenotype, which supported by findings that tr...
Toxoplasma gondii is an intracellular obligate parasite. Although most cases of toxoplasmosis go und...
Toxoplasmosis is an ubiquitous anthropozoonosis induced by Toxoplasma gondii. Despite of several res...
International audience: A piperidinyl-benzimidazolidinone scaffold has been found in the structure o...
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifet...
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifet...
Toxoplasmosis is an opportunistic disease caused by the protozoan parasite Toxoplasma gondii. The pa...
Toxoplasma gondii, an apicomplexan parasite affecting one third of the world’s population, causes th...
Apicomplexa are a large group of pathogenic parasites, which cause major infectious diseases includi...
P Holland Alday,1 Joseph Stone Doggett1,2 1Division of Infectious Diseases, Oregon Health & Sci...
Apicomplexan infections cause substantial morbidity and mortality, worldwide. New, improved therapie...
Apicomplexan infections cause substantial morbidity and mortality, worldwide. New, improved therapie...
Cytochrome bc1 inhibitors have been broadly studied as human and veterinary medicines and agricultur...
Toxoplasmosis is a parasitic disease caused by the globally distributed protozoan parasite Toxoplasm...
Toxoplasma gondii is an intracellular parasite that infects 30% of the world’s population. Toxoplasm...
International audienceToxoplasma gondii is a cosmopolitan protozoan parasite which affects approxima...
Toxoplasma gondii is an intracellular obligate parasite. Although most cases of toxoplasmosis go und...
Toxoplasmosis is an ubiquitous anthropozoonosis induced by Toxoplasma gondii. Despite of several res...
International audience: A piperidinyl-benzimidazolidinone scaffold has been found in the structure o...
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifet...
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifet...
Toxoplasmosis is an opportunistic disease caused by the protozoan parasite Toxoplasma gondii. The pa...
Toxoplasma gondii, an apicomplexan parasite affecting one third of the world’s population, causes th...
Apicomplexa are a large group of pathogenic parasites, which cause major infectious diseases includi...
P Holland Alday,1 Joseph Stone Doggett1,2 1Division of Infectious Diseases, Oregon Health & Sci...
Apicomplexan infections cause substantial morbidity and mortality, worldwide. New, improved therapie...
Apicomplexan infections cause substantial morbidity and mortality, worldwide. New, improved therapie...
Cytochrome bc1 inhibitors have been broadly studied as human and veterinary medicines and agricultur...
Toxoplasmosis is a parasitic disease caused by the globally distributed protozoan parasite Toxoplasm...
Toxoplasma gondii is an intracellular parasite that infects 30% of the world’s population. Toxoplasm...
International audienceToxoplasma gondii is a cosmopolitan protozoan parasite which affects approxima...
Toxoplasma gondii is an intracellular obligate parasite. Although most cases of toxoplasmosis go und...
Toxoplasmosis is an ubiquitous anthropozoonosis induced by Toxoplasma gondii. Despite of several res...
International audience: A piperidinyl-benzimidazolidinone scaffold has been found in the structure o...