The highly controlled regulation of pancreatic hormone secretion is vital to keep the body’s glucose concentration at a constant level. Defects in the regulation of glucose levels are involved in several metabolic diseases, including type 2 diabetes and obesity. Leptin is a satiety hormone with important roles in the maintenance of body weight and glucose homeostasis. Mice that lack leptin (ob/ob) or the leptin receptor (db/db) are massively obese and have diabetes symptoms. Leptin has been demonstrated to have an effect on glucose homeostasis that is suggested to be secondary to the obesity these animals are suffering from. Currently, it is unclear how leptin regulates glucose homeostasis. Leptin mediates its effects by interaction with...
Obesity is a growing health problem concerning much of the human civilization. Fundamental research ...
The adipose tissue-derived hormone leptin regulates energy balance and neuroendocrine function. Resi...
The fat derived hormone leptin plays a crucial role in the normal maintenance of body weight and ene...
Aims/hypothesis The adipose tissue-derived hormone leptin plays an important role in the maintena...
SummaryThe hormone leptin plays a crucial role in maintenance of body weight and glucose homeostasis...
AbstractLeptin, the product of the ob gene, controls appetite through the hypothalamus and may affec...
In most cases of human obesity serum leptin levels are elevated, suggesting that reduced sensitivity...
SummaryLeptin has beneficial effects on glucose metabolism via actions in the hypothalamus, but the ...
SummaryLeptin activates the long form of the leptin receptor (LRb) to control feeding and neuroendoc...
SummaryLeptin plays a pivotal role in regulation of energy balance. Via unknown central pathways, le...
SummaryLeptin has pleiotropic effects on glucose homeostasis and feeding behavior. Here, we validate...
Abstract - Obesity is a disease which has become a global epidemic that is beginning to replace unde...
Leptin regulates food intake and energy expenditure by activating the long form of the leptin recept...
Leptin is secreted by the adipose tissue in proportion to fat stores and acts on the hypothalamus to...
SummarySuppressor of cytokine signaling-3 (Socs-3) negatively regulates the action of various cytoki...
Obesity is a growing health problem concerning much of the human civilization. Fundamental research ...
The adipose tissue-derived hormone leptin regulates energy balance and neuroendocrine function. Resi...
The fat derived hormone leptin plays a crucial role in the normal maintenance of body weight and ene...
Aims/hypothesis The adipose tissue-derived hormone leptin plays an important role in the maintena...
SummaryThe hormone leptin plays a crucial role in maintenance of body weight and glucose homeostasis...
AbstractLeptin, the product of the ob gene, controls appetite through the hypothalamus and may affec...
In most cases of human obesity serum leptin levels are elevated, suggesting that reduced sensitivity...
SummaryLeptin has beneficial effects on glucose metabolism via actions in the hypothalamus, but the ...
SummaryLeptin activates the long form of the leptin receptor (LRb) to control feeding and neuroendoc...
SummaryLeptin plays a pivotal role in regulation of energy balance. Via unknown central pathways, le...
SummaryLeptin has pleiotropic effects on glucose homeostasis and feeding behavior. Here, we validate...
Abstract - Obesity is a disease which has become a global epidemic that is beginning to replace unde...
Leptin regulates food intake and energy expenditure by activating the long form of the leptin recept...
Leptin is secreted by the adipose tissue in proportion to fat stores and acts on the hypothalamus to...
SummarySuppressor of cytokine signaling-3 (Socs-3) negatively regulates the action of various cytoki...
Obesity is a growing health problem concerning much of the human civilization. Fundamental research ...
The adipose tissue-derived hormone leptin regulates energy balance and neuroendocrine function. Resi...
The fat derived hormone leptin plays a crucial role in the normal maintenance of body weight and ene...