Add to ORKGThe design of sensors to monitor the activity state of specific protein kinases is challenging due to the complexity of eukaryotic kinomes. Here we describe a peptide-based photaffinity probe that specifically labels the active conformation of the Abl tyrosine kinase
New methods to monitor tyrosine kinase activity are critical for studying kinases in cell biology, d...
AbstractThe ability of Syk protein tyrosine kinase (PTK) to phosphorylate peptides, where tyrosine h...
The maintenance of a robust cell signaling network is critical to numerous cellular processes includ...
The design of sensors to monitor the activity state of specific protein kinases is challenging due t...
Protein tyrosine kinases are essential components of cell signaling pathways, as well as highly impo...
International audienceDevelopment of sensitive and selective strategies for detection of disease bio...
Protein kinases play central roles in almost all aspects of normal and abnormal cell functions. Ther...
International audienceProtein kinases (PKs) are established gameplayers in biological signalling pat...
Cell signaling is a complex web of protein-protein interactions, post translational modifications an...
AbstractTwo molecular sensors that specifically recognize ADP in a background of over 100-fold molar...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009.Vita. Cataloged fro...
Protein kinases are important regulators of cellular function, and the dynamics of their activities ...
A peptidase-resistant ABL kinase substrate was developed by identifying protease-susceptible bonds o...
Target identification of biologically active molecules such as natural products, synthetic small mo...
<p>The epidermal growth factor receptor (EGFR) and HER2 are two important tyrosine kinases that play...
New methods to monitor tyrosine kinase activity are critical for studying kinases in cell biology, d...
AbstractThe ability of Syk protein tyrosine kinase (PTK) to phosphorylate peptides, where tyrosine h...
The maintenance of a robust cell signaling network is critical to numerous cellular processes includ...
The design of sensors to monitor the activity state of specific protein kinases is challenging due t...
Protein tyrosine kinases are essential components of cell signaling pathways, as well as highly impo...
International audienceDevelopment of sensitive and selective strategies for detection of disease bio...
Protein kinases play central roles in almost all aspects of normal and abnormal cell functions. Ther...
International audienceProtein kinases (PKs) are established gameplayers in biological signalling pat...
Cell signaling is a complex web of protein-protein interactions, post translational modifications an...
AbstractTwo molecular sensors that specifically recognize ADP in a background of over 100-fold molar...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009.Vita. Cataloged fro...
Protein kinases are important regulators of cellular function, and the dynamics of their activities ...
A peptidase-resistant ABL kinase substrate was developed by identifying protease-susceptible bonds o...
Target identification of biologically active molecules such as natural products, synthetic small mo...
<p>The epidermal growth factor receptor (EGFR) and HER2 are two important tyrosine kinases that play...
New methods to monitor tyrosine kinase activity are critical for studying kinases in cell biology, d...
AbstractThe ability of Syk protein tyrosine kinase (PTK) to phosphorylate peptides, where tyrosine h...
The maintenance of a robust cell signaling network is critical to numerous cellular processes includ...