Successful treatment of a Streptococcus pneumoniae- associated haemolytic uraemic syndrome by eculizumab
- Jeantet, Guillaume
- Pernin, Vincent
- Brunot, Vincent
- Roccabianca, Arnaud
- Macombe, Anouk
- Szwarc, Ilan
- Klouche, Kada
- Loirat, Chantal
- Mourad, Georges
- Fremeaux-Bacchi, Veronique
- Le Quintrec, Moglie
DOIAbstract
International audienceHaemolytic uraemic syndrome (HUS) is a rare complication of invasive infection by Streptococcus pneumoniae (SP-HUS), especially in adults. Here we report an unusual case of a 53-year-old man presenting SP-HUS with severe multivisceral involvement. After failure of supportive care and plasma exchanges, eculizumab (anti-C5 antibody) resulted in a favourable outcome
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