Primary focal segmental glomerulosclerosis in adults: presentation, prevalence and treatment outcomes in patients at Charlotte Maxeke Johannesburg Academic Hospital

A Research Report submitted to the Faculty of Health Sciences, University of the Witwatersrand, in partial fulfillment of the requirements for the degree of Master of Medicine in Internal Medicine Johannesburg, 2015The presenting features and treatment of patients with Primary Focal Segmental Glomerulosclerosis (FSGS) were characterised in this study. Methods Adults with primary FSGS at Charlotte Maxeke Johannesburg Hospital from 2001-2010 were reviewed. 38 patients were identified; 8 were lost to follow-up after presentation and 30 were further characterised in terms of outcomes. Analysis was performed of the clinical presentation, therapeutic and cumulative outcomes. A p