Aerosol and microbial microclimate of clean rooms

Master´s thesis deals with the issue of internal microclimate of clean rooms. The experimental part focuses on aerosol and microbial microclimate. Different operating and intervention rooms were measured and then evaluated whether the cleanroom would comply with the standard cleanliness class even in normal operation after previous validations. The microbial examination of different clean spaces investigated the extent to which the exact passive fall method and its evaluation were time-dependent. From the data the correct desing of the air-conditioning system and its subsequent realization and regultion were verified. The theoretical part describes requirements for clean rooms according to SÚKL-LEK 17 and ČSN EN ISO 14644-1. In addition, a detailed methodology of the procedure of air-conditioning implementation is elaborated to the final validation and testing of clean rooms