Tumour necrosis factor (TNF) is one of the most important pro-inflammatory cytokines of the innate immune system. We compared the presence of anti-TNF activity in saliva or salivary gland extract from 11 tick species from the family Ixodidae and demonstrated it in genera Ixodes and Haemaphysalis. We also tested dynamics of this specific activity in Ixodes ricinus saliva. The highest effect of saliva appears at the end of feeding period. Significance of anti-TNF activity for tick feeding and transmission of tick-borne pathogens is discussed
Ticks (Acari: Ixodidae) are bloodsucking ectoparasitic arthropods of human and veterinary medical im...
Tick saliva contains a lot of molecules with antihemostatic properties, which can affect host's hemo...
It has been established, that tick saliva shifted the cytokine profile of the host immune response t...
Rezková, Markéta, Kopecký, Jan (2017): Anti-tumour necrosis factor activity in saliva of various tic...
The skin site at which ticks attach to their hosts to feed is the critical interface between the tic...
Tick saliva plays a vital role in blood-feeding, including manipulation of the host response to tick...
The saliva of ticks (Suborder Ixodida) is critical to their survival as parasites. A tick bite shoul...
Ticks are bloodsucking ectoparasites that cause great damage to host organisms, so these ectoparasit...
Ticks are blood feeding parasites that secrete a number of immunomodulatory factors to evade host im...
International audienceAs long-term pool feeders, ticks have developed myriad strategies to remain di...
Tick saliva plays a vital role in blood-feeding, including manipulation of the host response to tick...
Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid engorgement. The co...
Secretions of the tick salivary glands are essential to the successful completion of the prolonged f...
Ixodid ticks require comparatively large bloodmeals for their development and survival. Blood-feedin...
Ticks use proteinaceous molecules contained in their saliva to suppress immune response of the host ...
Ticks (Acari: Ixodidae) are bloodsucking ectoparasitic arthropods of human and veterinary medical im...
Tick saliva contains a lot of molecules with antihemostatic properties, which can affect host's hemo...
It has been established, that tick saliva shifted the cytokine profile of the host immune response t...
Rezková, Markéta, Kopecký, Jan (2017): Anti-tumour necrosis factor activity in saliva of various tic...
The skin site at which ticks attach to their hosts to feed is the critical interface between the tic...
Tick saliva plays a vital role in blood-feeding, including manipulation of the host response to tick...
The saliva of ticks (Suborder Ixodida) is critical to their survival as parasites. A tick bite shoul...
Ticks are bloodsucking ectoparasites that cause great damage to host organisms, so these ectoparasit...
Ticks are blood feeding parasites that secrete a number of immunomodulatory factors to evade host im...
International audienceAs long-term pool feeders, ticks have developed myriad strategies to remain di...
Tick saliva plays a vital role in blood-feeding, including manipulation of the host response to tick...
Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid engorgement. The co...
Secretions of the tick salivary glands are essential to the successful completion of the prolonged f...
Ixodid ticks require comparatively large bloodmeals for their development and survival. Blood-feedin...
Ticks use proteinaceous molecules contained in their saliva to suppress immune response of the host ...
Ticks (Acari: Ixodidae) are bloodsucking ectoparasitic arthropods of human and veterinary medical im...
Tick saliva contains a lot of molecules with antihemostatic properties, which can affect host's hemo...
It has been established, that tick saliva shifted the cytokine profile of the host immune response t...