Colorectal Cancer Incidence And Mortality In Mainland Portugal (2007-2011)

Abstract publicado em: Gac Sanit. 2018;32(Espec Congr):7-140. http://gacetasanitaria.org/es-pdf-X0213911118629693Background/Objectives: Colorectal cancer is one of most common cancers in the world. That’s also the reality in Portugal where has the second highest cancer incidence rate for both sexes. With this in mind, is important to study colorectal cancer’s incidence and mortality evo-lution and to define measures that diminish the effect of this disease. One relevant issue in this analysis is to identify their spatial patterns and to find explanations to them. Our work’s main goal is to describe and compare spatial patterns of incidence and mortality by colorectal cancer, by sex, at mainland Portugal municipalities in 2007-2011.Methods: Cancer data were collected at Regional Oncologic Regis-tries (ROR). Mortality and Population data were available at Statistics Portugal (INE). All data were aggregated by municipalities and disag-gregated by sex and 17 quinquennial age groups – from 0-4 to 80 and more years old. We used Besag, York and Mollié (BYM) model to com-pute relative risk (RR) and posterior probability (PP). The choice of the geographic unit of analysis and applied model were based on results of our previous published researches.Results: Geographical distribution of incidence and mortality RR present spatial differences around mainland Portugal. Moreover, spatial patterns of incidence RR and PP are more heterogeneous than mortality RR and PP patterns. Colorectal cancer’s incidence RR is higher at Norte and at west coast municipalities. Mortality RR’s maps, in turn, present fewer municipalities classified in extreme classes than incidence’s maps. LVT and Alentejo stand out as the regions with higher mortality’s RR, particularly to men. PP maps strengthen higher heterogeneity of inci-dence comparing to mortality. Incidence maps show high PP values clus-tering in Norte and Centro coast and in LVT. Mortality maps display a wide cluster at LVT and Alentejo, particularly remarkable at men map.Conclusions/Recommendations: We found geographical differ-ences in colorectal cancer’s incidence and mortality rates. It is impor-tant to take into account these patterns when establishing measures to fight cancer. It is relevant to take particularly attention to the mu-nicipalities which register high values of both incidence and mortal-ity RR and PP.