This article is the result of a round-table discussion organised by ESMO Open in Vienna in December 2017. Its purpose is to discuss the background and advances in the evidence regarding cyclin-dependent kinase 4/6 inhibitors (palbociclib, ribociclib and abemaciclib) in the treatment of metastatic and early-stage breast cancer and to explore what the key open research questions are and next steps should be.SCOPUS: re.jinfo:eu-repo/semantics/publishe
Targeted therapies such as Cyclin Dependent Kinase 4 and 6 (CDK 4/6) inhibitors have improved the pr...
Despite significant advances in early detection and treatment, breast cancer still remains a major c...
Despite significant advances in early detection and treatment, breast cancer still remains a major c...
Introduction: Dysregulated cellular proliferation, one of the hallmarks of cancer, is mediated by ab...
Abstract Uncontrolled cell division is the hallmark of cancers. Full understanding of cell cycle reg...
Purpose: To provide an overview of clinical data supporting the use of cyclin-dependent kinases 4 an...
The emergence of cyclin-dependent kinase (CDK) 4 and 6 inhibitors has brought a new approach in the ...
Breast Cancer (BC) is the second most common type of cancer worldwide and displays the highest cance...
peer reviewedIn December 2017, ESMO Open-Cancer Horizons convened a round-table discussion on the ba...
The cyclin-dependent kinase (CDK) 4/6 inhibitors belong to a new class of drugs that interrupt proli...
Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, inte...
Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, inte...
Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, inte...
Breast Cancer is the most common type of cancer worldwide. Scientific advances and new ways of treat...
AbstractThe cyclin D-cyclin dependent kinase (CDK) 4/6-inhibitor of CDK4 (INK4)-retinoblastoma (Rb) ...
Targeted therapies such as Cyclin Dependent Kinase 4 and 6 (CDK 4/6) inhibitors have improved the pr...
Despite significant advances in early detection and treatment, breast cancer still remains a major c...
Despite significant advances in early detection and treatment, breast cancer still remains a major c...
Introduction: Dysregulated cellular proliferation, one of the hallmarks of cancer, is mediated by ab...
Abstract Uncontrolled cell division is the hallmark of cancers. Full understanding of cell cycle reg...
Purpose: To provide an overview of clinical data supporting the use of cyclin-dependent kinases 4 an...
The emergence of cyclin-dependent kinase (CDK) 4 and 6 inhibitors has brought a new approach in the ...
Breast Cancer (BC) is the second most common type of cancer worldwide and displays the highest cance...
peer reviewedIn December 2017, ESMO Open-Cancer Horizons convened a round-table discussion on the ba...
The cyclin-dependent kinase (CDK) 4/6 inhibitors belong to a new class of drugs that interrupt proli...
Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, inte...
Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, inte...
Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, inte...
Breast Cancer is the most common type of cancer worldwide. Scientific advances and new ways of treat...
AbstractThe cyclin D-cyclin dependent kinase (CDK) 4/6-inhibitor of CDK4 (INK4)-retinoblastoma (Rb) ...
Targeted therapies such as Cyclin Dependent Kinase 4 and 6 (CDK 4/6) inhibitors have improved the pr...
Despite significant advances in early detection and treatment, breast cancer still remains a major c...
Despite significant advances in early detection and treatment, breast cancer still remains a major c...