CITATION: Whitfield, M. G., et al. 2015. A global perspective on pyrazinamide resistance: systematic review and meta- analysis. PLoS ONE, 10(7):1-16, doi:10.1371/journal.pone.0133869.The original publication is available at http://journals.plos.org/plosoneBackground: Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to eradicate persister bacilli. The worldwide burden of PZA resistance remains poorly described. Methods Systematic PubMed, Science Direct and Scopus searches for articles reporting phenotypic (liquid culture drug susceptibility testing or pyrazinamidase activity assays) and/or genotypic (polymerase chain reaction or DNA sequencing) PZA resistance. Global and regional summary estimate...
AbstractAims and objectivesThe aim of this study is to determine the prevalence of pyrazinamide (PZA...
SETTING: The World Health Organization (WHO) recommends the inclusion of pyrazinamide (PZA) in treat...
Pyrazinamide (PZA), is regarded as an important agent in the management of multi-drug resistant tube...
Background Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability t...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
<div><p>Background</p><p>Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its un...
Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to eradicate...
Pyrazinamide resistance is largely unknown in the spectrum of drug resistant phenotypes. We summariz...
Pyrazinamide resistance is largely unknown in the spectrum of drug resistant phenotypes. We summariz...
BACKGROUND: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights ...
Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of action a...
BACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the e...
IntroductionPyrazinamide (PZA) is essential in tuberculosis (TB) treatment. We describe the prevalen...
AbstractAims and objectivesThe aim of this study is to determine the prevalence of pyrazinamide (PZA...
SETTING: The World Health Organization (WHO) recommends the inclusion of pyrazinamide (PZA) in treat...
Pyrazinamide (PZA), is regarded as an important agent in the management of multi-drug resistant tube...
Background Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability t...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
<div><p>Background</p><p>Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its un...
Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to eradicate...
Pyrazinamide resistance is largely unknown in the spectrum of drug resistant phenotypes. We summariz...
Pyrazinamide resistance is largely unknown in the spectrum of drug resistant phenotypes. We summariz...
BACKGROUND: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights ...
Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of action a...
BACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the e...
IntroductionPyrazinamide (PZA) is essential in tuberculosis (TB) treatment. We describe the prevalen...
AbstractAims and objectivesThe aim of this study is to determine the prevalence of pyrazinamide (PZA...
SETTING: The World Health Organization (WHO) recommends the inclusion of pyrazinamide (PZA) in treat...
Pyrazinamide (PZA), is regarded as an important agent in the management of multi-drug resistant tube...