Parameter screening in ethanolic extraction of total phenolics extracts from Sesamum Indicum L. using single factor and two-level factorial design

Sesamum indicum L. is an herbaceous plant from the family of Padaliacea grown in tropical and subtropical part of the world. There are up to 20 species from this genus, usually grown due to the high protein from their seeds and the edibility of their leaves. It is a self-pollinated plants usually grown on annual basis with multi-branching stem network with an average height of about 1.25m [1]. This plant has shown a remarkable use as food and in disease prevention and this is due to the presence of a significant amount of gamma-tocopherol and vitamin-E.. Nahar and Rokonuzzaman, [2] tested the ethanolic extracts of Sesamum indicum on an acid-induced writhing modeled mice. Their study confirmed the ability of the extracts to inhibit writhing as comparable with the standard drug called ibuprofen. The aforementioned medicinal properties of the extracts against oxidative diseases are dependent on the total phenolic content present in different extraction conditions