In order to describe a cell at molecular level, a notion of a “gene” is neither necessary nor helpful. It is sufficient to consider the molecules (i.e., chromosomes, transcripts, proteins) and their interactions to describe cellular processes. The downside of the resulting high resolution is that it becomes very tedious to address features on the organismal and phenotypic levels with a language based on molecular terms. Looking for the missing link between biological disciplines dealing with different levels of biological organization, we suggest to return to the original intent behind the term “gene”. To this end, we propose to investigate whether a useful notion of “gene” can be constructed based on an underlying notion of function, and w...
In the last few years, the lack of a unitary notion of gene across biological sciences has troubled ...
International audienceWe focus here on two prevalent meanings of the word gene in research articles....
Historians of genetics agree that multiple conceptions of the gene have coexisted at each stages in ...
In order to describe a cell at molecular level, a notion of a “gene” is neither necessary nor helpfu...
In order to describe a cell at molecular level, a notion of a "gene" is neither necessary nor helpfu...
Abstract In order to describe a cell at molecular level, a notion of a ‘‘gene’ ’ is neither necessar...
The term “gene” was originally used as a purely theoretical concept. After discovery of DNA structur...
In this paper, we address both ontological and epistemological problems related to the concept of ‘g...
International audience'Gene' has become a vague and ill-defined concept. To set the stage for mathem...
The molecular concept of gene has been subject, in recent decades, to a constant process of theoreti...
"Gene" is a theoretical term. Like all theoretical terms, it applies to many different domains of re...
Challenges to the gene concept have shown the difficulty of preserving the classical molecular conce...
The precise elucidation of the gene concept has become the subject of intense discussion in light of...
One of the most important goals of the post-genomic era is to understand the different sources of mo...
The univocal correspondence between one gene and one polypeptide has been challenged by many example...
In the last few years, the lack of a unitary notion of gene across biological sciences has troubled ...
International audienceWe focus here on two prevalent meanings of the word gene in research articles....
Historians of genetics agree that multiple conceptions of the gene have coexisted at each stages in ...
In order to describe a cell at molecular level, a notion of a “gene” is neither necessary nor helpfu...
In order to describe a cell at molecular level, a notion of a "gene" is neither necessary nor helpfu...
Abstract In order to describe a cell at molecular level, a notion of a ‘‘gene’ ’ is neither necessar...
The term “gene” was originally used as a purely theoretical concept. After discovery of DNA structur...
In this paper, we address both ontological and epistemological problems related to the concept of ‘g...
International audience'Gene' has become a vague and ill-defined concept. To set the stage for mathem...
The molecular concept of gene has been subject, in recent decades, to a constant process of theoreti...
"Gene" is a theoretical term. Like all theoretical terms, it applies to many different domains of re...
Challenges to the gene concept have shown the difficulty of preserving the classical molecular conce...
The precise elucidation of the gene concept has become the subject of intense discussion in light of...
One of the most important goals of the post-genomic era is to understand the different sources of mo...
The univocal correspondence between one gene and one polypeptide has been challenged by many example...
In the last few years, the lack of a unitary notion of gene across biological sciences has troubled ...
International audienceWe focus here on two prevalent meanings of the word gene in research articles....
Historians of genetics agree that multiple conceptions of the gene have coexisted at each stages in ...