Let (R, [special characters omitted]) be a local complete intersection, that is, a local ring whose [special characters omitted]-adic completion is the quotient of a complete regular local ring by a regular sequence. Let M and N be finitely generated R-modules. This dissertation concerns the vanishing of [special characters omitted](M, N) and [special characters omitted](M, N). In this context, M satisfies Serre\u27s condition ( Sn) if and only if M is an n th syzygy. The complexity of M is the least nonnegative integer r such that the nth Betti number of M is bounded by a polynomial of degree r − 1 for all sufficiently large n. We use this notion of Serre\u27s condition and complexity to study the vanishing of [special characters omitted](...