Combinatorial configurations have significant applications in many areas, such as in the design of experiments, coding theory, computer architecture, and information storage and retrieval. In this work, we will concentrate on three types of combinatorial configurations: t-designs, perpendicular arrays, and $\lambda$-designs. On t-designs. Khosrovshahi and Ajoodani-Namini give a new method for extending t-designs with k = t + 1. They obtain a recursive construction for t-designs and for large sets. Here we generalize their results to the general case k $\ge$ t + 1, and construct a family of large sets of $3 - (v,5,{v-3\choose 2}/3)$ designs with $v = 9m + 4 (m = 1,2,3,\...).$ Further we show that there exists a large set of $4-(9m + 5,6,{9m+...