Prospective evaluation of rhinovirus infection in healthy young children
- N. Principi
- A. Zampiero
- M. Gambino
- A. Scala
- L. Senatore
- M. Lelii
- B. Ascolese
- C. Pelucchi
- S. Esposito
DOIAbstract
Background: Although the incidence of human rhinovirus (HRV) infection is highest in young, no study has yet been published concerning the types of HRV circulating in this population, the incidence of symptomatic infections due to the different types, or duration of shedding. Objectives: This prospective study evaluated the circulation of HRV species and types, and established the incidence of asymptomatic and symptomatic infections in young children. Study design: The study enrolled 93 healthy children aged <2 years, 88 of whom completed the follow-up of weekly household visits from November 2013 to February 2014. At each visit, a record was made of any signs and symptoms of acute infection, and a nasopharyngeal (NP) swab was taken in orde...
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