In the present bed rest (BR) study, 23 volunteers were randomized into 3 subgroups: 60 d BR control (Ctr); BR with resistive exercise (RE; lowerlimb load); and resistive vibration exercise (RVE; RE with superimposed vibration). The aim was to analyze by confocal and electron microscopy the effects of vibration on myofibril and filament integrity in soleus (Sol) and vastus lateralis (VL) muscle; differential proteomics of contractile, cytoskeletal, and costameric proteins (TN-C, ROCK1, and FAK); and expression of PGC1\u3b1 and atrophy-related master genes MuRF1 and MuRF2. RVE (but not RE) preserved myofiber size and phenotype in Sol and VL by overexpressing MYBPC1 (42%, P 650.01), WDR1 (39%, P 650.01), sarcosin (84%, P 650.01), and CKM (20%,...
Summary During and after prolonged bed rest, changes in bone metabolic markers occur within 3 days...
AbstractActivity-induced nitric oxide (NO) imbalance and “nitrosative stress” are proposed mechanism...
Protein S-nitrosylation prevented by resistive vibration exercise (RVE) in human skeletal muscle fol...
In the present bed rest (BR) study, 23 volunteers were randomized into 3 subgroups: 60 d BR control ...
Disuse-induced muscle atrophy is a major concern in aging, in neuromuscular diseases, post-traumatic...
Disuse-induced muscle atrophy is a major concern in aging, in neuromuscular diseases, post-traumatic...
The present investigation, the first in the field, was aimed at analyzing differentially, on individ...
The present investigation, the first in the field, was aimed at analyzing differentially, on individ...
International audienceMuscle atrophy is a deleterious consequence of physical inactivity and is asso...
Prolonged immobilization of the human body results in functional impairments and musculoskeletal sys...
IntroductionLong-term head-down bed rest (HDBR) results in musculoskeletal losses similar to those o...
International audienceSeveral studies have examined the effects of vibrations on muscle mass and per...
Following disuse, muscle fibre function goes through adaptations such as a loss of specific force (P...
Following disuse, muscle fibre function goes through adaptations such as a loss of specific force (P...
Several studies have examined the effects of vibrations on muscle mass and performance in young heal...
Summary During and after prolonged bed rest, changes in bone metabolic markers occur within 3 days...
AbstractActivity-induced nitric oxide (NO) imbalance and “nitrosative stress” are proposed mechanism...
Protein S-nitrosylation prevented by resistive vibration exercise (RVE) in human skeletal muscle fol...
In the present bed rest (BR) study, 23 volunteers were randomized into 3 subgroups: 60 d BR control ...
Disuse-induced muscle atrophy is a major concern in aging, in neuromuscular diseases, post-traumatic...
Disuse-induced muscle atrophy is a major concern in aging, in neuromuscular diseases, post-traumatic...
The present investigation, the first in the field, was aimed at analyzing differentially, on individ...
The present investigation, the first in the field, was aimed at analyzing differentially, on individ...
International audienceMuscle atrophy is a deleterious consequence of physical inactivity and is asso...
Prolonged immobilization of the human body results in functional impairments and musculoskeletal sys...
IntroductionLong-term head-down bed rest (HDBR) results in musculoskeletal losses similar to those o...
International audienceSeveral studies have examined the effects of vibrations on muscle mass and per...
Following disuse, muscle fibre function goes through adaptations such as a loss of specific force (P...
Following disuse, muscle fibre function goes through adaptations such as a loss of specific force (P...
Several studies have examined the effects of vibrations on muscle mass and performance in young heal...
Summary During and after prolonged bed rest, changes in bone metabolic markers occur within 3 days...
AbstractActivity-induced nitric oxide (NO) imbalance and “nitrosative stress” are proposed mechanism...
Protein S-nitrosylation prevented by resistive vibration exercise (RVE) in human skeletal muscle fol...