Vagus nerve stimulation in refractory epilepsy : New indications and outcome assessment
- C.E. Marras
- V. Chiesa
- A. De Benedictis
- A. Franzini
- M. Rizzi
- F. Villani
- F. Ragona
- L. Tassi
- A. Vignoli
- E. Freri
- N. Specchio
- G. Broggi
- M. Casazza
- M.P. Canevini
DOIAbstract
Although vagus nerve stimulation (VNS) is an effective alternative option for patients with refractory epilepsy unsuitable for conventional resective surgery, predictors of a better control of seizure frequency and severity are still unavailable. This prospective study reports on 39 patients, including 4 children affected by epilepsia partialis continua (EPC), who underwent VNS for refractory epilepsy. The overall seizure frequency outcome was classified into three groups according to reduction rate: 6575%, 6550%, and <50%. Engel and McHugh classifications were also used. The median follow-up period was 36months. A seizure reduction rate 6550% or EPC improvement was observed in 74% of the patients. Twenty-one out of 35 cases (60%) result...
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