The apoptosis inducing factor (AIF) is a mitochondrial NAD(H)-binding flavoprotein that, when released from the organelle in response to various stimuli, causes cell death (1). In addition to its role in caspase-independent apoptosis, AIF also plays an essential, although poorly understood, function in maintaining the functionality of oxidative phosphorylation. While AIF gene inactivation is embryonic lethal in mammals, downregulation of its expression causes myopathies and neurological abnormalities (1). Very recently, two distinct point mutations in human AIF gene were identified as responsible of human mitochondriopathies resulting in severe early encephalomyopathy (2) and prenatal ventriculomegaly (3), respectively. We have reproduced t...
Apoptosis-inducing factor (AIF) is a mitochondrial oxidoreductase that contributes to cell death pro...
The apoptosis-inducing factor (AIF) is a mitochondrial-flavoprotein that, after cell death induction...
International audienceApoptosis-inducing factor (AIF) is a NADH oxidase with a local redox function ...
Apoptosis inducing factor (AIF) is a Janus flavoprotein that plays opposite vital and lethal roles i...
Mitochondria fulfil two different functions, representing both the cell power engine and a checkpoin...
The apoptosis inducing factor (AIF) is a mitochondrial NAD-dependent flavoprotein, which, in additio...
The apoptosis-inducing factor (AIF) is a FAD-containing protein playing critical roles in caspase-in...
Numerous pro-apoptotic signal transducing molecules act on mitochondria and provoke the permeabiliza...
Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein with pro-life and pro-death activiti...
Beside its apoptotic function, the Apoptosis Inducing Factor (AIF), a highly conserved mitochondrial...
Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein with pro-life and pro-death activiti...
Apoptosis-Inducing Factor (AIF) is a protein involved in mitochondrial electron transport chain asse...
Apoptosis-inducing factor (AIF) is a mitochondrial oxidoreductase that contributes to cell death pro...
Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein, which translocates to the nucleus d...
International audienceObjectives: Apoptosis-Inducing Factor (AIF) is a protein involved in mitochond...
Apoptosis-inducing factor (AIF) is a mitochondrial oxidoreductase that contributes to cell death pro...
The apoptosis-inducing factor (AIF) is a mitochondrial-flavoprotein that, after cell death induction...
International audienceApoptosis-inducing factor (AIF) is a NADH oxidase with a local redox function ...
Apoptosis inducing factor (AIF) is a Janus flavoprotein that plays opposite vital and lethal roles i...
Mitochondria fulfil two different functions, representing both the cell power engine and a checkpoin...
The apoptosis inducing factor (AIF) is a mitochondrial NAD-dependent flavoprotein, which, in additio...
The apoptosis-inducing factor (AIF) is a FAD-containing protein playing critical roles in caspase-in...
Numerous pro-apoptotic signal transducing molecules act on mitochondria and provoke the permeabiliza...
Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein with pro-life and pro-death activiti...
Beside its apoptotic function, the Apoptosis Inducing Factor (AIF), a highly conserved mitochondrial...
Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein with pro-life and pro-death activiti...
Apoptosis-Inducing Factor (AIF) is a protein involved in mitochondrial electron transport chain asse...
Apoptosis-inducing factor (AIF) is a mitochondrial oxidoreductase that contributes to cell death pro...
Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein, which translocates to the nucleus d...
International audienceObjectives: Apoptosis-Inducing Factor (AIF) is a protein involved in mitochond...
Apoptosis-inducing factor (AIF) is a mitochondrial oxidoreductase that contributes to cell death pro...
The apoptosis-inducing factor (AIF) is a mitochondrial-flavoprotein that, after cell death induction...
International audienceApoptosis-inducing factor (AIF) is a NADH oxidase with a local redox function ...