Add to ORKGThe synthesis of a series of 6-(4R-phenyl)-5-hydroxymethyl-4,5-dihydro-3(2H)pyridazinones is reported. The compounds were evaluated for their oral antihypertensive activity in rats and some of them [(V b), R = NH2] and [(V c), R = NHCOCH3] were found to induce a high decrease in systolic blood pressure. Moreover all the compounds displayed an antithrombotic activity comparable to, or greater than, that of ASA
The inotropic and vasodilatory properties of 4,5-dihydro-6-phenylpyridazin--3(2H)-ones are well docu...
The synthesis of new benzylidenaminoguanidine compounds is described. Some of these compounds were t...
The synthesis of 3-(arylamino)-6,7-dihydro-6-methylpyrano[4,3-c]pyrazol-4(1H or 2H)-ones [I, R = (un...
The main objective present research work to synthesis, characterization and biological evaluation of...
New 5-aryl-6-methyl-4,5-dihydropyridazin-3(2H)ones (III) and related 5-aryl-6-methyl-pyridazin-3(2H)...
Some new 6-(substituted phenyl)-2-(4-substituted phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-...
The main objective present research work to synthesis, characterization and biological evaluation of...
3-Hydrazinocycloheptyl[1,2-c]pyridazine (4) and its hydrazone derivatives 3-[N1-(isopropylidene)]hyd...
The synthesis of N-substituted 4,5(3)-diphenyl-3(5)-pyrazoleamines by reaction of N-substituted 3-ox...
The preparation of a series of 1,4,5-trisubstituted pyrazoles is described. These compounds have bee...
698-701A series of 1, 4-dihydro-2, 6-dimethyl-4-{4-[3-(2-aminopyrazine/1-amino-4-methyl piperazine)-...
A series of heterocyclic compounds incorporating pyridazine moiety were for diverse biological activ...
The synthesis and evaluation of the biological activity of new 4-chloro-5-{4-[2-(2-methoxyphenoxy)-e...
1574-15796-(Substituted aryl)-4-methyl-2, 3-dihydropyridazin-3-ones are synthesized by cyclisation ...
A series of 2-(carbethoxypiperazinyl)- and 2-piperazinyl-1,8-naphthyridine derivatives, variously su...
The inotropic and vasodilatory properties of 4,5-dihydro-6-phenylpyridazin--3(2H)-ones are well docu...
The synthesis of new benzylidenaminoguanidine compounds is described. Some of these compounds were t...
The synthesis of 3-(arylamino)-6,7-dihydro-6-methylpyrano[4,3-c]pyrazol-4(1H or 2H)-ones [I, R = (un...
The main objective present research work to synthesis, characterization and biological evaluation of...
New 5-aryl-6-methyl-4,5-dihydropyridazin-3(2H)ones (III) and related 5-aryl-6-methyl-pyridazin-3(2H)...
Some new 6-(substituted phenyl)-2-(4-substituted phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-...
The main objective present research work to synthesis, characterization and biological evaluation of...
3-Hydrazinocycloheptyl[1,2-c]pyridazine (4) and its hydrazone derivatives 3-[N1-(isopropylidene)]hyd...
The synthesis of N-substituted 4,5(3)-diphenyl-3(5)-pyrazoleamines by reaction of N-substituted 3-ox...
The preparation of a series of 1,4,5-trisubstituted pyrazoles is described. These compounds have bee...
698-701A series of 1, 4-dihydro-2, 6-dimethyl-4-{4-[3-(2-aminopyrazine/1-amino-4-methyl piperazine)-...
A series of heterocyclic compounds incorporating pyridazine moiety were for diverse biological activ...
The synthesis and evaluation of the biological activity of new 4-chloro-5-{4-[2-(2-methoxyphenoxy)-e...
1574-15796-(Substituted aryl)-4-methyl-2, 3-dihydropyridazin-3-ones are synthesized by cyclisation ...
A series of 2-(carbethoxypiperazinyl)- and 2-piperazinyl-1,8-naphthyridine derivatives, variously su...
The inotropic and vasodilatory properties of 4,5-dihydro-6-phenylpyridazin--3(2H)-ones are well docu...
The synthesis of new benzylidenaminoguanidine compounds is described. Some of these compounds were t...
The synthesis of 3-(arylamino)-6,7-dihydro-6-methylpyrano[4,3-c]pyrazol-4(1H or 2H)-ones [I, R = (un...