Alzheimer Disease (AD) is characterized by the progressive deposition of \u3b2-amyloid in the parenchyma and cerebral microvasculature. The \u3b2-amyloid peptide derives from the metabolism of a larger precursor, Amyloid Precursor Protein (APP). This protein is present in central nervous system, but it is also expressed in peripheral tissues such as circulating cells. An alteration of the APP forms pattern in platelets has been recently reported in AD patients when compared to platelets both of control subjects or non AD patients (NADD). The accuracy of the assay to identify AD is high and decreased levels are found throughout the course of AD with a significant association with severity of symptoms. Moreover, a recent study has demonstrate...
Studies have shown that platelet APP ratio (representing the percentage of 120-130 kDa to 110 kDa is...
Alzheimer Disease (AD) is the most common neurodegenerative disorder worldwide, and account for 60% ...
Abstract Frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD) represent the most...
BACKGROUND: An altered pattern of amyloid precursor protein (APP) forms consisting in a reduced rat...
BACKGROUND: An altered pattern of amyloid precursor protein (APP) forms consisting in a reduced rati...
Background: An altered pattern of amyloid precursor protein (APP) forms consisting in a reduced rati...
Previous findings demonstrated an altered pattern of amyloid precursor protein (APP) forms in platel...
Alzheimer disease is a progressive neurodegenerative disease, characterised by a progressive cogniti...
Alzheimer disease is a progressive neurodegenerative disease, characterised by a progressive cogniti...
Platelets represent an important peripheral source of Amyloid Precursor Protein (APP). Three major A...
Background: Amyloid precursor protein (APP) forms with apparent molecular weights of 130, 110, and 1...
Previous findings demonstrated an altered pattern of amyloid precursor protein (APP) forms in platel...
Objective: To determine whether a differential level of platelet amyloid \u3b2 precursor protein (AP...
The processing of the amyloid precursor protein (APP) is a critical event in the formation of amyloi...
Context: Patients affected by sporadic Alzheimer disease (AD) show a significant alteration of amylo...
Studies have shown that platelet APP ratio (representing the percentage of 120-130 kDa to 110 kDa is...
Alzheimer Disease (AD) is the most common neurodegenerative disorder worldwide, and account for 60% ...
Abstract Frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD) represent the most...
BACKGROUND: An altered pattern of amyloid precursor protein (APP) forms consisting in a reduced rat...
BACKGROUND: An altered pattern of amyloid precursor protein (APP) forms consisting in a reduced rati...
Background: An altered pattern of amyloid precursor protein (APP) forms consisting in a reduced rati...
Previous findings demonstrated an altered pattern of amyloid precursor protein (APP) forms in platel...
Alzheimer disease is a progressive neurodegenerative disease, characterised by a progressive cogniti...
Alzheimer disease is a progressive neurodegenerative disease, characterised by a progressive cogniti...
Platelets represent an important peripheral source of Amyloid Precursor Protein (APP). Three major A...
Background: Amyloid precursor protein (APP) forms with apparent molecular weights of 130, 110, and 1...
Previous findings demonstrated an altered pattern of amyloid precursor protein (APP) forms in platel...
Objective: To determine whether a differential level of platelet amyloid \u3b2 precursor protein (AP...
The processing of the amyloid precursor protein (APP) is a critical event in the formation of amyloi...
Context: Patients affected by sporadic Alzheimer disease (AD) show a significant alteration of amylo...
Studies have shown that platelet APP ratio (representing the percentage of 120-130 kDa to 110 kDa is...
Alzheimer Disease (AD) is the most common neurodegenerative disorder worldwide, and account for 60% ...
Abstract Frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD) represent the most...