Nonspecific inflammatory bowel disease and smoking

  • S. Franceschi
  • E. Panza
  • C. La Vecchia
  • F. Parazzini
  • A. Decarli
  • G. Bianchi Porro
Publication date
March 1987
Publisher
Oxford University Press (OUP)
ISSN
1476-6256
Citation count (estimate)
79

Abstract

The authors assessed the relation between cigarette smoking and nonspecific inflammatory bowel disease in a case-control study of 124 cases of ulcerative colitis, 109 cases of Crohn's disease, and 250 age- and sex-matched control subjects in hospital for acute nongastric or intestinal conditions unrelated to smoking. For ulcerative colitis, the risk for current smoking compared with never smoking was 0.5, with a 95% confidence interval (Cl) of 0.3-1.0. They observed decreasing risk with increasing number of cigarettes smoked. The risk for ex-smokers, however, was greater than that for never smokers (relative risk = 2.7; 95% Cl = 1.5-4.9). The elevated risk of ulcerative colitis in ex-smoking in the presence of an overall lack of association...

Extracted data

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