Add to ORKGNatural products continue to be interesting building blocks for the preparation of different types of derivatives that could result noteworthy for their pharmacological activity. The use of epothilone A, camptothecin, thiocolchicine, taxol and cephalomannine as building blocks will be reported together with the biological evaluation. Two cases of synthesis of new collections of tyrosine kinases inhibitors will be presented. The biological activity of the obtained compounds reinforce the importance of modelling studies to guide the design of successful candidates and the value of the interdisciplinary approach
For over 40 years, natural products have served us well in combating cancer. The main sources of the...
The preparation and biological evaluation of a novel series of dimeric camptothecin derivatives are ...
Local and traditional knowledge has been the starting point for many successful drug development pro...
Natural products continue to be interesting building blocks for the preparation of different types o...
The use of pharmaceutically active natural products as building blocks for the generation of new ent...
We are involved in the synthesis of new compounds potentially able to inhibit different biological t...
The presentation will be focused on the different ongoing projects in the field of natural products ...
Cancer is one of the major deadly diseases globally. The alarming rise in the mortality rate due to ...
Traditional medicines, including Chinese herbal formulations, can serve as the source of potential n...
Traditional medicines, including Chinese herbal formulations, can serve as the source of potential n...
Natural products continue to be a source for the discovery of drugs and drug leads even from ancient...
Epothilones are bacterial macrolides with potent microtubule-stabilizing and antiproliferative activ...
The preparation and biological evaluation of a novel series of dimeric camptothecin derivatives are ...
The increasing prevalence of drug resistant and/or high-risk cancers indicate further drug discovery...
Cancer is not just a disease; It is a complex of diseases that leads to abnormal physiology, metabol...
For over 40 years, natural products have served us well in combating cancer. The main sources of the...
The preparation and biological evaluation of a novel series of dimeric camptothecin derivatives are ...
Local and traditional knowledge has been the starting point for many successful drug development pro...
Natural products continue to be interesting building blocks for the preparation of different types o...
The use of pharmaceutically active natural products as building blocks for the generation of new ent...
We are involved in the synthesis of new compounds potentially able to inhibit different biological t...
The presentation will be focused on the different ongoing projects in the field of natural products ...
Cancer is one of the major deadly diseases globally. The alarming rise in the mortality rate due to ...
Traditional medicines, including Chinese herbal formulations, can serve as the source of potential n...
Traditional medicines, including Chinese herbal formulations, can serve as the source of potential n...
Natural products continue to be a source for the discovery of drugs and drug leads even from ancient...
Epothilones are bacterial macrolides with potent microtubule-stabilizing and antiproliferative activ...
The preparation and biological evaluation of a novel series of dimeric camptothecin derivatives are ...
The increasing prevalence of drug resistant and/or high-risk cancers indicate further drug discovery...
Cancer is not just a disease; It is a complex of diseases that leads to abnormal physiology, metabol...
For over 40 years, natural products have served us well in combating cancer. The main sources of the...
The preparation and biological evaluation of a novel series of dimeric camptothecin derivatives are ...
Local and traditional knowledge has been the starting point for many successful drug development pro...