Olfactory bulb kindling rates were studied in two inbred strains of genetically seizure-prone mice (DBA/2 and E1) and in three non-epileptic inbred strains [C57BL/6 (B6), ddY, and C3H/He (C3H)]. None of the DBA/2 mice had been stimulated to seizure before or during the kindling and all mice were studied at 4-6 weeks of age, before development of spontaneous or movement-induced seizure activity in the E1 strain. The audiogenically seizure-susceptible DBA/2 mice required the fewest number of stimulations to reach stage 5 seizure (mean \ub1 SE = 4.0 \ub1 0.6). The nonepileptic C3H mice required the most stimulations to reach stage 5 seizures (22.6 \ub1 1.4). Kindling rates for B6 (9.6 \ub1 0.6), E1 (14.8 \ub1 1.1), and ddY (18.5 \ub1 1.0) stra...
International audienceObjective: Mouse models of sudden unexpected death in epileptic patients (SUDE...
Epidemiological data and gene association studies suggest a genetic predisposition to developing epi...
We previously established two strains of Mongolian gerbil: a seizure-sensitive strain, established b...
Epilepsy is one of the most common but genetically complex neurological disorders in humans. Identif...
Febrile seizures (FS) are the most common seizure type in children and recurrent FS are a risk facto...
Febrile Seizures (FS) are the most common seizure type in children and recurrent FS are a risk facto...
The recombinant inbred mouse strain, SWXL-4, exhibits tonic-clonic and generalized seizures similar ...
The electroconvulsive threshold (ECT) test is used commonly in the screening of anti-epileptic drugs...
Absence epilepsy is a common form of idiopathic generalized epilepsy whose etiology is poorly unders...
The EL mouse strain provides a polygenic model for epilepsy. Previous mapping experiments between EL...
To characterize the genetic basis of spike-wave discharges (SWDs) detected by electroencephalography...
In conclusion, we have discussed a reverse genetics approach to studying seizure disorders in mice (...
Myoclonus is often observed in epilepsy. It is characterized by sudden involuntary shock-like moveme...
The EL/Suz (EL) mouse is a strain that is highly susceptible to convulsive seizures after repeated s...
DBA/2J (D2) and C57BL/6J (B6) mice exhibit differential sensitivity to seizures induced by various c...
International audienceObjective: Mouse models of sudden unexpected death in epileptic patients (SUDE...
Epidemiological data and gene association studies suggest a genetic predisposition to developing epi...
We previously established two strains of Mongolian gerbil: a seizure-sensitive strain, established b...
Epilepsy is one of the most common but genetically complex neurological disorders in humans. Identif...
Febrile seizures (FS) are the most common seizure type in children and recurrent FS are a risk facto...
Febrile Seizures (FS) are the most common seizure type in children and recurrent FS are a risk facto...
The recombinant inbred mouse strain, SWXL-4, exhibits tonic-clonic and generalized seizures similar ...
The electroconvulsive threshold (ECT) test is used commonly in the screening of anti-epileptic drugs...
Absence epilepsy is a common form of idiopathic generalized epilepsy whose etiology is poorly unders...
The EL mouse strain provides a polygenic model for epilepsy. Previous mapping experiments between EL...
To characterize the genetic basis of spike-wave discharges (SWDs) detected by electroencephalography...
In conclusion, we have discussed a reverse genetics approach to studying seizure disorders in mice (...
Myoclonus is often observed in epilepsy. It is characterized by sudden involuntary shock-like moveme...
The EL/Suz (EL) mouse is a strain that is highly susceptible to convulsive seizures after repeated s...
DBA/2J (D2) and C57BL/6J (B6) mice exhibit differential sensitivity to seizures induced by various c...
International audienceObjective: Mouse models of sudden unexpected death in epileptic patients (SUDE...
Epidemiological data and gene association studies suggest a genetic predisposition to developing epi...
We previously established two strains of Mongolian gerbil: a seizure-sensitive strain, established b...