Add to ORKGRATIONALE Acute and chronic exposure to particulate air pollution has been associated with increased risk of cardiovascular and respiratory disease. Processes related to cardiorespiratory outcomes, such as oxidative stress, atherosclerosis, aging have been associated with lower global DNA methylation content in blood DNA. Whether DNA methylation is modified by air particle exposure has never been tested. METHODS We estimated global DNA methylation through analysis of LINE1 and Alu repeated elements in 1,006 blood DNA samples from the Normative Aging Study (NAS), a repeated measure investigation of elderly men in Boston. DNA methylation was measured analysis of bisulfite-treated blood DNA by PCR-Pyrosequencing. We used mixed models to estima...
BACKGROUND: Long-term air pollution exposure is negatively associated with lung function, yet the me...
Long-term exposure to air pollution has been associated with several adverse health effects includin...
Long-term exposure to air pollution has been associated with several adverse health effects includin...
Exposure to particulate air pollution, particularly to traffic pollutants, has been associated with ...
Abstract RATIONALE: Exposure to particulate air pollution has been related to increased hospitaliza...
Background: Short-term exposure to particulate air pollution has been associated with increased hos...
Air pollution exposure is estimated to contribute to approximately seven million early deaths every ...
Background: Exposure to Particulate Matter (PM) from ambient and occupational sources has been asso...
BACKGROUND: Epidemiological studies have reported associations between particulate matter (PM) conce...
DNA methylation is a potential pathway linking air pollution to disease. Studies indicate that psych...
One of the potential mechanisms linking air pollution to health effects is through changes in DNA-me...
Background and Objective: DNA methylation is a potential pathway linking environmental exposures to ...
Exposure to airborne particulate matter (PM) has been associated with detrimental health effects. DN...
BACKGROUND: Altered patterns of gene expression mediate the effects of particulate matter (PM) on hu...
Background One of the potential mechanisms linking air pollution to health effects is through change...
BACKGROUND: Long-term air pollution exposure is negatively associated with lung function, yet the me...
Long-term exposure to air pollution has been associated with several adverse health effects includin...
Long-term exposure to air pollution has been associated with several adverse health effects includin...
Exposure to particulate air pollution, particularly to traffic pollutants, has been associated with ...
Abstract RATIONALE: Exposure to particulate air pollution has been related to increased hospitaliza...
Background: Short-term exposure to particulate air pollution has been associated with increased hos...
Air pollution exposure is estimated to contribute to approximately seven million early deaths every ...
Background: Exposure to Particulate Matter (PM) from ambient and occupational sources has been asso...
BACKGROUND: Epidemiological studies have reported associations between particulate matter (PM) conce...
DNA methylation is a potential pathway linking air pollution to disease. Studies indicate that psych...
One of the potential mechanisms linking air pollution to health effects is through changes in DNA-me...
Background and Objective: DNA methylation is a potential pathway linking environmental exposures to ...
Exposure to airborne particulate matter (PM) has been associated with detrimental health effects. DN...
BACKGROUND: Altered patterns of gene expression mediate the effects of particulate matter (PM) on hu...
Background One of the potential mechanisms linking air pollution to health effects is through change...
BACKGROUND: Long-term air pollution exposure is negatively associated with lung function, yet the me...
Long-term exposure to air pollution has been associated with several adverse health effects includin...
Long-term exposure to air pollution has been associated with several adverse health effects includin...