Background: Combination chemotherapy yields better response rates which do not always lead to a survival advantage. The aim of this study was to investigate whether the reported differences in the efficacy and toxicity of monotherapy with doxorubicin (DOX) versus combination therapy with cisplatin (CDDP) in endometrial adenocarcinoma lead to significant advantage in favour of the combination. Patients and methods: Eligible patients had histologically-proven advanced and/or recurrent endometrial adenocarcinoma and were chemo-naïve. Treatment consisted of either DOX 60 mg/m2 alone or CDDP 50 mg/m2 added to DOX 60 mg/m2, every 4 weeks. Results: A total of 177 patients were entered and median follow-up is 7.1 years. The combination DOX–...
PURPOSE: The primary objective of this phase I trial was to determine the feasibility of administeri...
Purpose To compare the clinical and pathologic response rates of doxorubicin and cyclophosphamide (A...
OBJECTIVE: The optimal sequence of administering chemotherapy (CT) and radiation treatment (RT) in w...
BACKGROUND: Combination chemotherapy yields better response rates which do not always lead to a surv...
Background: Combination chemotherapy yields better response rates which do not always lead to a surv...
wit- a vanced or recurrent endometrial carcinoma no longer amenable to therapy with surgery, radioth...
Endometrial cancer generally has a good prognosis because most cases are diagnosed in stage I. It is...
The combination of cisplatin (50 mg/m2), epirubicin (60 mg/m2), and cyclophosphamide (600 mg/m2) (PE...
One hundred and twenty-five patients with advanced epithelial ovarian cancer (EOC) were postsurgical...
PurposeLimitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment of endomet...
PURPOSE: Three previous mitomycin-cisplatin-based chemotherapy trials conducted within the EORTC Gyn...
The objective of our study was to determine whether adjuvant chemotherapy combined with postoperativ...
Purpose/Objective(s): There remains no definitive consensus on the optimal sequencing of adjuvant ch...
OBJECTIVE: The optimal sequence of administering chemotherapy (CT) and radiation treatment (RT) in w...
Patients with high-risk endometrial carcinoma (stage IcG3, IIG3 with myometrial invasion > 50%, and ...
PURPOSE: The primary objective of this phase I trial was to determine the feasibility of administeri...
Purpose To compare the clinical and pathologic response rates of doxorubicin and cyclophosphamide (A...
OBJECTIVE: The optimal sequence of administering chemotherapy (CT) and radiation treatment (RT) in w...
BACKGROUND: Combination chemotherapy yields better response rates which do not always lead to a surv...
Background: Combination chemotherapy yields better response rates which do not always lead to a surv...
wit- a vanced or recurrent endometrial carcinoma no longer amenable to therapy with surgery, radioth...
Endometrial cancer generally has a good prognosis because most cases are diagnosed in stage I. It is...
The combination of cisplatin (50 mg/m2), epirubicin (60 mg/m2), and cyclophosphamide (600 mg/m2) (PE...
One hundred and twenty-five patients with advanced epithelial ovarian cancer (EOC) were postsurgical...
PurposeLimitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment of endomet...
PURPOSE: Three previous mitomycin-cisplatin-based chemotherapy trials conducted within the EORTC Gyn...
The objective of our study was to determine whether adjuvant chemotherapy combined with postoperativ...
Purpose/Objective(s): There remains no definitive consensus on the optimal sequencing of adjuvant ch...
OBJECTIVE: The optimal sequence of administering chemotherapy (CT) and radiation treatment (RT) in w...
Patients with high-risk endometrial carcinoma (stage IcG3, IIG3 with myometrial invasion > 50%, and ...
PURPOSE: The primary objective of this phase I trial was to determine the feasibility of administeri...
Purpose To compare the clinical and pathologic response rates of doxorubicin and cyclophosphamide (A...
OBJECTIVE: The optimal sequence of administering chemotherapy (CT) and radiation treatment (RT) in w...