BACKGROUND : bullous pemphigoid (BP) is a blistering skin disease caused by autoantibodies to hemidesmosomal proteins, with eosinophils participating in blister formation. Eosinophils are a source of tissue factor (TF), an initiator of blood coagulation OBJECTIVES : to evaluate the local and systemic activation of coagulation in BP METHODS : we studied 20 patients with active BP (eight re-evaluated during remission) and 40 controls. The coagulation markers prothrombin fragment F1+2 and d-dimer were measured in the plasma of all subjects and in both plasma and blister fluid of patients with BP. TF was evaluated immunohistochemically in skin specimens from the 20 patients and in 20 normal samples RESULTS : F1+2 and d-dimer levels were higher ...
Several lines of evidence indicate that the immune system, inflammation, and coagulation are simulta...
Activation of blood coagulation has been demonstrated in bullous pemphigoid (BP), a rare autoimmune ...
Activation of blood coagulation has been demonstrated in bullous pemphigoid (BP), a rare autoimmune ...
Background: Bullous pemphigoid (BP) is an inflammatory blistering skin disease mainly affecting elde...
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality an...
Coagulation activation has been demonstrated in two prototypic autoimmune skin diseases, chronic aut...
Evidence exists that the immune and coagulation systems are simultaneously activated in some systemi...
Coagulation activation has been demonstrated in two prototypic autoimmune skin diseases, chronic au...
The immune system and blood coagulation are simultaneously activated in several inflammatory systemi...
Coagulation activation has been demonstrated in two prototypic autoimmune skin diseases, chronic aut...
Dermatitis herpetiformis (DH) and bullous pemphigoid (BP) are skin diseases associated with eosinoph...
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering skin disease and is ch...
Background: Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease characterized b...
Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP1...
Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP1...
Several lines of evidence indicate that the immune system, inflammation, and coagulation are simulta...
Activation of blood coagulation has been demonstrated in bullous pemphigoid (BP), a rare autoimmune ...
Activation of blood coagulation has been demonstrated in bullous pemphigoid (BP), a rare autoimmune ...
Background: Bullous pemphigoid (BP) is an inflammatory blistering skin disease mainly affecting elde...
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality an...
Coagulation activation has been demonstrated in two prototypic autoimmune skin diseases, chronic aut...
Evidence exists that the immune and coagulation systems are simultaneously activated in some systemi...
Coagulation activation has been demonstrated in two prototypic autoimmune skin diseases, chronic au...
The immune system and blood coagulation are simultaneously activated in several inflammatory systemi...
Coagulation activation has been demonstrated in two prototypic autoimmune skin diseases, chronic aut...
Dermatitis herpetiformis (DH) and bullous pemphigoid (BP) are skin diseases associated with eosinoph...
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering skin disease and is ch...
Background: Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease characterized b...
Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP1...
Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP1...
Several lines of evidence indicate that the immune system, inflammation, and coagulation are simulta...
Activation of blood coagulation has been demonstrated in bullous pemphigoid (BP), a rare autoimmune ...
Activation of blood coagulation has been demonstrated in bullous pemphigoid (BP), a rare autoimmune ...