Exposure to particulate air pollution, particularly to traffic pollutants, has been associated with increased risk of cancer in humans. Oxidative stress, such as that induced by particulate exposure, have been associated with lower global DNA methylation content in blood DNA, and decreases in global DNA methylation have been found in cancer subjects in both malignant tissues and blood DNA. Whether DNA methylation is modified by air particle exposure has never been tested. We estimated global DNA methylation through analysis of LINE-1 and Alu repeated elements in 1,006 blood DNA samples from the Normative Aging Study (NAS), a repeated measure investigation of elderly men in Boston. DNA methylation was measured analysis of bisulfite-treated...
DNA methylation changes are potential pathways of environmentally induced health effects. We investi...
Background One of the potential mechanisms linking air pollution to health effects is through change...
BACKGROUND: Many epidemiological studies have shown that particulate matter (PM) concentrations are ...
RATIONALE Acute and chronic exposure to particulate air pollution has been associated with increased...
Abstract RATIONALE: Exposure to particulate air pollution has been related to increased hospitaliza...
Air pollution exposure is estimated to contribute to approximately seven million early deaths every ...
Background: Exposure to Particulate Matter (PM) from ambient and occupational sources has been asso...
One of the potential mechanisms linking air pollution to health effects is through changes in DNA-me...
Studies have indicated that air pollution, including surface-level ozone (O3), can significantly inf...
BACKGROUND: Epidemiological studies have reported associations between particulate matter (PM) conce...
Background: Short-term exposure to particulate air pollution has been associated with increased hos...
BACKGROUND: Altered patterns of gene expression mediate the effects of particulate matter (PM) on hu...
There is compelling evidence that particulate matter (PM) increases lung cancer risk by triggering s...
Long-term exposure to air pollution has been associated with several adverse health effects includin...
DNA methylation is a potential pathway linking air pollution to disease. Studies indicate that psych...
DNA methylation changes are potential pathways of environmentally induced health effects. We investi...
Background One of the potential mechanisms linking air pollution to health effects is through change...
BACKGROUND: Many epidemiological studies have shown that particulate matter (PM) concentrations are ...
RATIONALE Acute and chronic exposure to particulate air pollution has been associated with increased...
Abstract RATIONALE: Exposure to particulate air pollution has been related to increased hospitaliza...
Air pollution exposure is estimated to contribute to approximately seven million early deaths every ...
Background: Exposure to Particulate Matter (PM) from ambient and occupational sources has been asso...
One of the potential mechanisms linking air pollution to health effects is through changes in DNA-me...
Studies have indicated that air pollution, including surface-level ozone (O3), can significantly inf...
BACKGROUND: Epidemiological studies have reported associations between particulate matter (PM) conce...
Background: Short-term exposure to particulate air pollution has been associated with increased hos...
BACKGROUND: Altered patterns of gene expression mediate the effects of particulate matter (PM) on hu...
There is compelling evidence that particulate matter (PM) increases lung cancer risk by triggering s...
Long-term exposure to air pollution has been associated with several adverse health effects includin...
DNA methylation is a potential pathway linking air pollution to disease. Studies indicate that psych...
DNA methylation changes are potential pathways of environmentally induced health effects. We investi...
Background One of the potential mechanisms linking air pollution to health effects is through change...
BACKGROUND: Many epidemiological studies have shown that particulate matter (PM) concentrations are ...