Six years befor the present study we performed a retrospective study of 114 subjects presenting with asymptomatic / oligosymptomatic hyperckemia (raised creatine kinase blood levels), a diagnosis being made in 21 of them. We now present the results of a long-term follow-up in 55 of the still undiagnosed 93 individuals. Most of them have remained asymptomatic and did not develop specific neuromuscular disorders. One subject became frankly symptomatic manifesting limb-girdle weakness. A diagnosis of dystrophinopathy carrier and one of possible type I SMA carrier were indirectly made in another two subjects. Almost all subjects still have hyperckemia, though the mean creatine kinase (CK) value is lower than before. CK levels have become normal...
To summarize the etiology and clinical characteristics of children with myopathic elevated creatine ...
International audienceRegarding the frequency of muscular complains with the use of tyrosine kinase ...
Persistent hyperCKemia results from muscle dysfunction often attributed to genetic alterations of mu...
Persistent high creatine kinase (CK) levels may reflect underlying subclinical myopathies. In most c...
Increased activity of the enzyme creatine kinase (CK) in serum is not infrequently encountered in ro...
Elevated creatine kinase (hyper-CKemia) has been observed in small number of patients with hyponatre...
OBJECTIVE: To provide evidence-based guidelines to general neurologists for the assessment of patien...
Twenty-one patients with incidental hypertransaminasaemia who were eventually diagnosed as muscular ...
Areas of general agreement: Total creatine kinase (CK) levels depend on age, gender, race, muscle ma...
Persistent elevation of serum creatine kinase (CK) in individuals with normal neurological and labor...
To provide evidence-based guidelines to general neurologists for the assessment of patients with pau...
AREAS OF GENERAL AGREEMENT: Total creatine kinase (CK) levels depend on age, gender, race, muscle ma...
A 49-year-old man had an 8-year history of persistent, isolated elevation of serum creatine kinase (...
Sporadic inclusion body myositis (sIBM) usually manifests with painless weakness of the hand, finger...
Background: Rhabdomyolysis is a potentially fatal condition that can be triggered by a variety of in...
To summarize the etiology and clinical characteristics of children with myopathic elevated creatine ...
International audienceRegarding the frequency of muscular complains with the use of tyrosine kinase ...
Persistent hyperCKemia results from muscle dysfunction often attributed to genetic alterations of mu...
Persistent high creatine kinase (CK) levels may reflect underlying subclinical myopathies. In most c...
Increased activity of the enzyme creatine kinase (CK) in serum is not infrequently encountered in ro...
Elevated creatine kinase (hyper-CKemia) has been observed in small number of patients with hyponatre...
OBJECTIVE: To provide evidence-based guidelines to general neurologists for the assessment of patien...
Twenty-one patients with incidental hypertransaminasaemia who were eventually diagnosed as muscular ...
Areas of general agreement: Total creatine kinase (CK) levels depend on age, gender, race, muscle ma...
Persistent elevation of serum creatine kinase (CK) in individuals with normal neurological and labor...
To provide evidence-based guidelines to general neurologists for the assessment of patients with pau...
AREAS OF GENERAL AGREEMENT: Total creatine kinase (CK) levels depend on age, gender, race, muscle ma...
A 49-year-old man had an 8-year history of persistent, isolated elevation of serum creatine kinase (...
Sporadic inclusion body myositis (sIBM) usually manifests with painless weakness of the hand, finger...
Background: Rhabdomyolysis is a potentially fatal condition that can be triggered by a variety of in...
To summarize the etiology and clinical characteristics of children with myopathic elevated creatine ...
International audienceRegarding the frequency of muscular complains with the use of tyrosine kinase ...
Persistent hyperCKemia results from muscle dysfunction often attributed to genetic alterations of mu...