Diastereoselective synthesis of beta-hydroxy sulfoxides: enzymatic and biomimetic approaches

Stereoselectivities of up to 98% have been found in the enzymic synthesis of b-hydroxy sulfoxides catalyzed by cyclohexanone monooxygenase (CHMO). The diastereoselectivity of the "one-pot" prepn. of the title compds. in the presence of bovine serum albumin has also been investigated