Fascin, an actin-bundling protein involved in cell motility, has been shown to be upregulated in several types of carcinomas. In this study, we investigated the expression of fascin in 228 advanced colonic adenocarcinoma patients with a long follow-up. Fascin expression was compared with several clinicopathologic parameters and survival. Overall, fascin immunoreactivity was detected in 162 (71%) tumours with a prevalence for right-sided tumours (P<0.001). Fascin correlated significantly with sex, tumour grade and stage, mucinous differentiation, number of metastatic lymph nodes, extranodal tumour extension, and the occurrence of distant metastases. Patients with fascin-expressing tumours experienced a shorter disease-free and overall surviv...
Invasion and metastasis are major reason for poor prognosis of digestive system carcinoma patients. ...
Previous cell biological studies demonstrate that the actin bundling protein fascin1 regulates cell ...
Background: Colorectal cancer (CRC) is the fourth most common human malignancies worldwide. Fascin1 ...
Fascin, an actin-bundling protein, is expressed in many neoplasms including colorectal cancer. It is...
BACKGROUND: Fascin is an actin bundling protein with roles in the formation of cell protrusions and ...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in the malig...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in the malig...
PURPOSE: The purpose of this study was to investigate the significance of fascin expression in color...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in th...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in th...
Introduction. Fascins are a group of proteins taking part in the maintenance of a proper structur...
Levels of the actin bundling protein fascin correlate with invasion and metastasis and reveal progno...
Levels of the actin bundling protein fascin correlate with invasion and metastasis and reveal progno...
Previous cell biological studies demonstrate that the actin bundling protein fascin1 regulates cell ...
Previous cell biological studies demonstrate that the actin bundling protein fascin1 regulates cell ...
Invasion and metastasis are major reason for poor prognosis of digestive system carcinoma patients. ...
Previous cell biological studies demonstrate that the actin bundling protein fascin1 regulates cell ...
Background: Colorectal cancer (CRC) is the fourth most common human malignancies worldwide. Fascin1 ...
Fascin, an actin-bundling protein, is expressed in many neoplasms including colorectal cancer. It is...
BACKGROUND: Fascin is an actin bundling protein with roles in the formation of cell protrusions and ...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in the malig...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in the malig...
PURPOSE: The purpose of this study was to investigate the significance of fascin expression in color...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in th...
Background: Fascin is overexpressed in many cancers, including colorectal, but its role in th...
Introduction. Fascins are a group of proteins taking part in the maintenance of a proper structur...
Levels of the actin bundling protein fascin correlate with invasion and metastasis and reveal progno...
Levels of the actin bundling protein fascin correlate with invasion and metastasis and reveal progno...
Previous cell biological studies demonstrate that the actin bundling protein fascin1 regulates cell ...
Previous cell biological studies demonstrate that the actin bundling protein fascin1 regulates cell ...
Invasion and metastasis are major reason for poor prognosis of digestive system carcinoma patients. ...
Previous cell biological studies demonstrate that the actin bundling protein fascin1 regulates cell ...
Background: Colorectal cancer (CRC) is the fourth most common human malignancies worldwide. Fascin1 ...