The effects of strength training on muscle wasting, fat mass and quality of life in men with Prostate Cancer undergoing Androgen Deprivation Therapy: a meta-analysis.

• In 2013, the probability of a man developing prostate cancer (PCa) was 1 in 6, sitting on top of the charts as the single most common area for men to develop cancer [4]. • The most common form of treatment in New Zealand is a funded prescription medicine called Zoladex (Goserelin), an anti androgen medication that reduces the production of testosterone that can fuel the growth of the cancer. • Suppression of testosterone production can be related with considerable side effects including muscle atrophy (sarcopenia/wasting), changes in weight (typically an increase in weight from oestrogen levels dominating in the body due to the lack of testosterone production). • Physical activity focussing on strength training in particular has been proposed as a favourable strategy to reverse the side effects of Androgen deprivation therapy (ADT), especially that of muscle wasting and changes in body composition