Hydrostatic pressure culture system for human chondrocyte cultivation and stimulation in gellan gum hydrogel disks

[Excerpt] Cartilage tissue loss, resulting from injury or disease, is a major health problem worldwide. Tissue Engineering (TE) has a great potential for the treatment of vast number of pathologies. In this regard, bioreactor systems are used as frameworks for studying fundamental aspects of cell response and tissue development, as well as scale–up platforms for industrial application. […]