International audienceIt is now well established that there were four Hox gene clusters in the genome of the last common ancestor of extant gnathostomes. To better understand the evolution of the organization and expression of these genomic regions, we have studied the Hox gene clusters of a shark (Scyliorhinus canicula). We sequenced 225,580 expressed sequence tags from several embryonic cDNA libraries. Blast searches identified corresponding transcripts to almost all the HoxA, HoxB, and HoxD cluster genes. No HoxC transcript was identified, suggesting that this cluster is absent or highly degenerate. Using Hox gene sequences as probes, we selected and sequenced seven clones from a bacterial artificial chromosome library covering the compl...
The study of Hox clusters and genes provides insights into the evolution of genomic regulation of de...
The study of Hox clusters and genes provides insights into the evolution of genomic regulation of de...
A new group of vertebrate Hox genes, Hox14, has been discovered in two fish, the horn shark and the ...
International audienceIt is now well established that there were four Hox gene clusters in the genom...
Comparisons of DNA sequences among evolutionarily distantly related genomes permit identification of...
AbstractHox genes, responsible for regional specification along the anteroposterior axis in embryoge...
The statistical analysis of phylogenetic footprints in the two known horn shark Hox clusters and the...
The Hox gene cluster system is highly conserved among jawed-vertebrates. Specifically, the coding re...
Hox genes exert fundamental roles for proper regional specification along the main rostro-caudal axi...
Hox genes code for transcription factors that play a major role in the development of all animal phy...
Due to their high degree of conservation, comparisons of DNA sequences among evolutionarily distantl...
SYNOPSIS. The early origin of four vertebrate Hox gene clusters during the evo-lution of gnathostome...
The early origin of four vertebrate Hox gene clusters during the evolution of gnathostomes was likel...
Due to their high degree of conservation, comparisons of DNA sequences among evolutionarily distant...
Teleost fishes have extra Hox gene clusters owing to shared or lineage-specific genome duplication e...
The study of Hox clusters and genes provides insights into the evolution of genomic regulation of de...
The study of Hox clusters and genes provides insights into the evolution of genomic regulation of de...
A new group of vertebrate Hox genes, Hox14, has been discovered in two fish, the horn shark and the ...
International audienceIt is now well established that there were four Hox gene clusters in the genom...
Comparisons of DNA sequences among evolutionarily distantly related genomes permit identification of...
AbstractHox genes, responsible for regional specification along the anteroposterior axis in embryoge...
The statistical analysis of phylogenetic footprints in the two known horn shark Hox clusters and the...
The Hox gene cluster system is highly conserved among jawed-vertebrates. Specifically, the coding re...
Hox genes exert fundamental roles for proper regional specification along the main rostro-caudal axi...
Hox genes code for transcription factors that play a major role in the development of all animal phy...
Due to their high degree of conservation, comparisons of DNA sequences among evolutionarily distantl...
SYNOPSIS. The early origin of four vertebrate Hox gene clusters during the evo-lution of gnathostome...
The early origin of four vertebrate Hox gene clusters during the evolution of gnathostomes was likel...
Due to their high degree of conservation, comparisons of DNA sequences among evolutionarily distant...
Teleost fishes have extra Hox gene clusters owing to shared or lineage-specific genome duplication e...
The study of Hox clusters and genes provides insights into the evolution of genomic regulation of de...
The study of Hox clusters and genes provides insights into the evolution of genomic regulation of de...
A new group of vertebrate Hox genes, Hox14, has been discovered in two fish, the horn shark and the ...