The present invention relates to a antibiotically active compounds characterized by general formula (I), wherein X1, BB, BC, BD, BE and X2 are building blocks with D1, D2, D3, D4 or D5 being linkers which comprise carbon, sulphur, nitrogen, phosphor and/or oxygen atoms and which are covalently connecting the moities BA and BB, BB and BC, BC and BD, BD and BE and BE and BF, respectively, and wherein in particular the building block BC comprises an amino acid derivative. The invention relates further to said compounds for use in a method of treatment of diseases, in particular for use in a method of treatment of bacterial infections
The present invention relates to certain compounds of formula (I) wherein - Ar is (Ar1) or (Ar2) and...
The recent and persistent emergence of antibiotic-resistant bacterial strains, typically used clinic...
Albicidin is a potent inhibitor of prokaryotic DNA gyrase, produced by the sugarcane pathogenic bact...
Albicidin is a recently described natural product that strongly inhibits bacterial DNA gyrase. The p...
Three gene clusters that together encode albicidin biosynthesis, the complete gene DNA sequences, an...
Albicidin is a toxin and an antibiotic produced by the slow-growing bacterium Xanthomonas albilinean...
In the light of the rapid emergence and spread of multidrug-resistant (MDR) pathogens and the dwindl...
Albicidin is a potent DNA gyrase inhibitor produced by the sugarcane pathogenic bacterium Xanthomona...
Albicidin is a potent DNA gyrase inhibitor produced by the sugarcane pathogenic bacterium Xanthomona...
Natural products represent an important source of potential novel antimicrobial drug leads. Low prod...
Xanthomonas albilineans, which causes leaf scald disease of sugarcane, produces a highly potent path...
The natural product albicidin is a highly potent inhibitor of bacterial DNA gyrase. Its outstanding ...
Albicidin is a potent antibacterial oligoaromatic peptide that is susceptible to the protease AlbD, ...
Aujourd’hui la résistance aux antibiotiques constitue l’une des plus graves menaces pesant sur la sa...
En inhibant la différenciation des chloroplastes, l'albicidine joue un rôle majeur dans le pouvoir p...
The present invention relates to certain compounds of formula (I) wherein - Ar is (Ar1) or (Ar2) and...
The recent and persistent emergence of antibiotic-resistant bacterial strains, typically used clinic...
Albicidin is a potent inhibitor of prokaryotic DNA gyrase, produced by the sugarcane pathogenic bact...
Albicidin is a recently described natural product that strongly inhibits bacterial DNA gyrase. The p...
Three gene clusters that together encode albicidin biosynthesis, the complete gene DNA sequences, an...
Albicidin is a toxin and an antibiotic produced by the slow-growing bacterium Xanthomonas albilinean...
In the light of the rapid emergence and spread of multidrug-resistant (MDR) pathogens and the dwindl...
Albicidin is a potent DNA gyrase inhibitor produced by the sugarcane pathogenic bacterium Xanthomona...
Albicidin is a potent DNA gyrase inhibitor produced by the sugarcane pathogenic bacterium Xanthomona...
Natural products represent an important source of potential novel antimicrobial drug leads. Low prod...
Xanthomonas albilineans, which causes leaf scald disease of sugarcane, produces a highly potent path...
The natural product albicidin is a highly potent inhibitor of bacterial DNA gyrase. Its outstanding ...
Albicidin is a potent antibacterial oligoaromatic peptide that is susceptible to the protease AlbD, ...
Aujourd’hui la résistance aux antibiotiques constitue l’une des plus graves menaces pesant sur la sa...
En inhibant la différenciation des chloroplastes, l'albicidine joue un rôle majeur dans le pouvoir p...
The present invention relates to certain compounds of formula (I) wherein - Ar is (Ar1) or (Ar2) and...
The recent and persistent emergence of antibiotic-resistant bacterial strains, typically used clinic...
Albicidin is a potent inhibitor of prokaryotic DNA gyrase, produced by the sugarcane pathogenic bact...