Add to ORKGHuman DDX3 is a DEAD (Asp-Glu-Ala-Asp)-box RNA helicase that appears to be a prime target for viral manipulation. While two viruses that manifest major global health threats, HIV and HCV (hepatitis C virus), utilize DDX3 for their replication, other viruses inhibit DDX3’s newly identified function in innate antiviral signalling. This review discusses the role of DDX3 in antiviral immunity and its inhibition or exploitation by different viruses
Hepatitis C Virus (HCV) is a major cause of chronic hepatitis, with present estimates predicting tha...
The DEAD-box helicase DDX3 has suggested func-tions in innate immunity, mRNA translocation and trans...
Targeting cellular cofactors instead of viral enzymes represents a new strategy to combat infectious...
Human DDX3 is a DEAD (Asp-Glu-Ala-Asp)-box RNA helicase that appears to be a prime target for viral ...
The human DEAD-box RNA helicase DDX3 has been implicated to play a role in the whole repertoire of ...
Artículo de publicación ISIAsp-Glu-Ala-Asp (DEAD)-box polypeptide 3, or DDX3, belongs to the DEAD-bo...
DDX3 is a cellular ATP-dependent RNA helicase involved in different aspects of RNA metabolism rangin...
DDX3 is an RNA helicase that has been shown to have a range of nuclear and cytoplasmic functions, in...
During infection, our immune system triggers drastic but highly regulated changes in gene activity t...
This short review is focused on enzymatic properties of human ATP‐dependent RNA helicase DDX3 and th...
The human RNA helicase DDX3X is a real multifaceted enzyme. Like all the other DEAD-box proteins of ...
Viral infections inflict many serious human diseases with very high mortality rates. New drug-resist...
Compounds currently used for the treatment of HIV-1 Infections are targeted to viral proteins. Howev...
Compounds currently used for the treatment of HIV-1 Infections are targeted to viral proteins. Howev...
Innate immunity serves as the first barrier against virus infection. DEAD (Glu-Asp-Ala-Glu) box RNA ...
Hepatitis C Virus (HCV) is a major cause of chronic hepatitis, with present estimates predicting tha...
The DEAD-box helicase DDX3 has suggested func-tions in innate immunity, mRNA translocation and trans...
Targeting cellular cofactors instead of viral enzymes represents a new strategy to combat infectious...
Human DDX3 is a DEAD (Asp-Glu-Ala-Asp)-box RNA helicase that appears to be a prime target for viral ...
The human DEAD-box RNA helicase DDX3 has been implicated to play a role in the whole repertoire of ...
Artículo de publicación ISIAsp-Glu-Ala-Asp (DEAD)-box polypeptide 3, or DDX3, belongs to the DEAD-bo...
DDX3 is a cellular ATP-dependent RNA helicase involved in different aspects of RNA metabolism rangin...
DDX3 is an RNA helicase that has been shown to have a range of nuclear and cytoplasmic functions, in...
During infection, our immune system triggers drastic but highly regulated changes in gene activity t...
This short review is focused on enzymatic properties of human ATP‐dependent RNA helicase DDX3 and th...
The human RNA helicase DDX3X is a real multifaceted enzyme. Like all the other DEAD-box proteins of ...
Viral infections inflict many serious human diseases with very high mortality rates. New drug-resist...
Compounds currently used for the treatment of HIV-1 Infections are targeted to viral proteins. Howev...
Compounds currently used for the treatment of HIV-1 Infections are targeted to viral proteins. Howev...
Innate immunity serves as the first barrier against virus infection. DEAD (Glu-Asp-Ala-Glu) box RNA ...
Hepatitis C Virus (HCV) is a major cause of chronic hepatitis, with present estimates predicting tha...
The DEAD-box helicase DDX3 has suggested func-tions in innate immunity, mRNA translocation and trans...
Targeting cellular cofactors instead of viral enzymes represents a new strategy to combat infectious...