Add to ORKGA structural model for the active site of phosphoesterases, enzymes that degrade organophosphate neurotoxins, has been synthesised. The ligand 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid (H(3)L1) and two Zn(ii) complexes have been prepared and characterised as and The ligand (H(3)L1) and complex were characterised through (1)H NMR, (13)C NMR, mass spectroscopy and microanalysis. The X-ray crystal structure of revealed a tetramer of dinuclear complexes, bridged by two phosphate molecules and bifurcating acetic acid arms. Functional studies of the zinc complex with the substrate bis(4-nitrophenyl)phosphate (bNPP) determined the complex with HL1(2-) to be a competent ...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
A structural model for the active site of phosphoesterases, enzymes that degrade organophosphate neu...
A structural model for the active site of phosphoesterases, enzymes that degrade organophosphate neu...
A structural model for the active site of phosphoesterases, enzymes that degrade organophosphate neu...
The dinuclear complex [Zn2(DPCPMP)(pivalate)](ClO4), where DPCPMP is the new unsymmetrical ligand [2...
To mimic the active sites of the hydrolytic enzyme zinc phosphotriesterase, a new dinucleating unsym...
To mimic the active sites of the hydrolytic enzyme zinc phosphotriesterase, a new dinucleating unsym...
International audienceDinuclear zinc(II) complexes [Zn2(bpmp)(µ-OH)](ClO4)2 (1) and [Zn2(bpmp)(H2O)2...
A series of dinuclear [Zn2(L1)2X2] (1\u20133) and mononuclear [Zn(HL2)X2] complexes (4\u20136), (X =...
di-Zinc(II) complexes of the ligands 2,6-bis((bis(2-methoxyethyl)amino)methyl)-4-methylphenol (HL1),...
We report two asymmetric ligands for the generation of structural and functional dinuclear metal com...
Several new polydentate and potentially dinucleating ligands have been synthesized in order to model...
The unsymmetrical dinucleating ligand 2-(N-isopropyl-N-((2-pyridyl)methyl)aminomethyl)-6-(N-(carboxy...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
A structural model for the active site of phosphoesterases, enzymes that degrade organophosphate neu...
A structural model for the active site of phosphoesterases, enzymes that degrade organophosphate neu...
A structural model for the active site of phosphoesterases, enzymes that degrade organophosphate neu...
The dinuclear complex [Zn2(DPCPMP)(pivalate)](ClO4), where DPCPMP is the new unsymmetrical ligand [2...
To mimic the active sites of the hydrolytic enzyme zinc phosphotriesterase, a new dinucleating unsym...
To mimic the active sites of the hydrolytic enzyme zinc phosphotriesterase, a new dinucleating unsym...
International audienceDinuclear zinc(II) complexes [Zn2(bpmp)(µ-OH)](ClO4)2 (1) and [Zn2(bpmp)(H2O)2...
A series of dinuclear [Zn2(L1)2X2] (1\u20133) and mononuclear [Zn(HL2)X2] complexes (4\u20136), (X =...
di-Zinc(II) complexes of the ligands 2,6-bis((bis(2-methoxyethyl)amino)methyl)-4-methylphenol (HL1),...
We report two asymmetric ligands for the generation of structural and functional dinuclear metal com...
Several new polydentate and potentially dinucleating ligands have been synthesized in order to model...
The unsymmetrical dinucleating ligand 2-(N-isopropyl-N-((2-pyridyl)methyl)aminomethyl)-6-(N-(carboxy...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...
It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role ...