Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketonuria (PKU) have often been associated with metabolic control and its history. For the present study executive functioning (EF) was assessed in 21 PKU patients during childhood (T1, mean age 10.4 years, SD = 2.0) and again in adulthood (T2, mean age 25.8 years, SD = 2.3). At T2 additional assessments of EF in daily life and mental health were performed. Childhood (i.e. 0-12 years) blood phenylalanine was significantly related to cognitive flexibility, executive motor control, EF in daily life and mental health in adulthood (i.e. at T2). Patients with a greater increase in phenylalanine levels after the age of 12 performed more poorly on EF-ta...
Patients with treated phenylketonuria (PKU) can have subtle deficits in intellect, academic skills, ...
Phenylketonuria (PKU) is an inherited metabolic disease which, if left untreated, usually results in...
Previous studies have suggested that cognitive and psychosocial underfunctioning in early-treated ad...
Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketo...
Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketo...
Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketo...
Objective: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
Objective: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
OBJECTIVE: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
Abstract Background Even though early dietary management of phenylketonuria (PKU) successfully preve...
OBJECTIVE: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
BACKGROUND: Phenylketonuria (PKU) is an autosomal recessive inherited disorder characterised by a de...
This article presents a new Dutch multicenter study ("PKU-COBESO") into cognitive and behavioral seq...
Patients with treated phenylketonuria (PKU) can have subtle deficits in intellect, academic skills, ...
Phenylketonuria (PKU) is an inherited metabolic disease which, if left untreated, usually results in...
Previous studies have suggested that cognitive and psychosocial underfunctioning in early-treated ad...
Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketo...
Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketo...
Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketo...
Objective: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
Objective: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
OBJECTIVE: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
Abstract Background Even though early dietary management of phenylketonuria (PKU) successfully preve...
OBJECTIVE: Despite early dietary treatment phenylketonuria patients have lower IQ and poorer executi...
BACKGROUND: Phenylketonuria (PKU) is an autosomal recessive inherited disorder characterised by a de...
This article presents a new Dutch multicenter study ("PKU-COBESO") into cognitive and behavioral seq...
Patients with treated phenylketonuria (PKU) can have subtle deficits in intellect, academic skills, ...
Phenylketonuria (PKU) is an inherited metabolic disease which, if left untreated, usually results in...
Previous studies have suggested that cognitive and psychosocial underfunctioning in early-treated ad...