The striking correlation between genome topology and transcriptional activity has for decades made researchers revisit the question, "Does form follow function, or does function follow form?" In a new study, Hug et al. address this question by comparing the timing of zygotic genome activation to the emergence of genome structures during Drosophila embryogenesis
Contemplating how a single cell can turn into the trillions of specialized cells that make a human b...
Summary: Genome architecture has emerged as a critical element of transcriptional regulation, althou...
Regulation of gene expression is a complex process that requires the action of DNA elements such as ...
The striking correlation between genome topology and transcriptional activity has for decades made r...
The striking correlation between genome topology and transcriptional activity has for decades made r...
During development or in response to environmental stimuli, eukaryotic genes change both their expre...
The fusion of two transcriptionally silent gametes, egg and sperm, generates a totipotent zygote tha...
International audienceBackground; In all Metazoa, transcription is inactive during the first mitotic...
After fertilization, the embryonic genome is inactive until transcription is initiated during the ma...
The eukaryotic core promoter is an essential regulatory part of the genome. Its sequence dictates th...
International audienceTransmission of active transcriptional states from mother to daughter cells ha...
Early development is punctuated by a series of pervasive and fast paced transitions. These events re...
Control of metazoan embryogenesis shifts from maternal to zygotic gene products as the zygotic genom...
International audienceHow transcriptional bursting relates to gene regulation is a central question ...
BACKGROUND: Site-specific transcription factors (TFs) are coordinators of developmental and physiolo...
Contemplating how a single cell can turn into the trillions of specialized cells that make a human b...
Summary: Genome architecture has emerged as a critical element of transcriptional regulation, althou...
Regulation of gene expression is a complex process that requires the action of DNA elements such as ...
The striking correlation between genome topology and transcriptional activity has for decades made r...
The striking correlation between genome topology and transcriptional activity has for decades made r...
During development or in response to environmental stimuli, eukaryotic genes change both their expre...
The fusion of two transcriptionally silent gametes, egg and sperm, generates a totipotent zygote tha...
International audienceBackground; In all Metazoa, transcription is inactive during the first mitotic...
After fertilization, the embryonic genome is inactive until transcription is initiated during the ma...
The eukaryotic core promoter is an essential regulatory part of the genome. Its sequence dictates th...
International audienceTransmission of active transcriptional states from mother to daughter cells ha...
Early development is punctuated by a series of pervasive and fast paced transitions. These events re...
Control of metazoan embryogenesis shifts from maternal to zygotic gene products as the zygotic genom...
International audienceHow transcriptional bursting relates to gene regulation is a central question ...
BACKGROUND: Site-specific transcription factors (TFs) are coordinators of developmental and physiolo...
Contemplating how a single cell can turn into the trillions of specialized cells that make a human b...
Summary: Genome architecture has emerged as a critical element of transcriptional regulation, althou...
Regulation of gene expression is a complex process that requires the action of DNA elements such as ...