Aim Whole slide images (WSIs) have stimulated a paradigm shift from conventional to digital pathology in several applications within pathology. Due to the fact that WSIs have not yet been approved for primary diagnostics, validating their use for different diagnostic purposes is still mandatory. The aim of this study was to test the validity of WSI in assessing human epidermal growth factor receptor 2 (HER2) status in breast cancer specimens using chromogenic in situ hybridisation (CISH). Materials and methods Ninety-six HER2 CISH slides were scored by two observers on a light microscope (400× viewing magnification) and on WSI (40× scanning magnification, one focus plane) with a minimum of 6 weeks washout period. The concordance between dig...
Aims: The objective of this study was to evaluate the accuracy, ease of use and reproducibility of c...
Aims: To establish whether core needle biopsy (CNB) specimens processed with an accelerated processi...
Background: With the emerging role of digital imaging in pathology and the application of automated ...
Aim Whole slide images (WSIs) have stimulated a paradigm shift from conventional to digital patholog...
Background: The use of digital whole slide imaging for human epidermal growth factor receptor 2 (HER...
Background: Optimization of workflow for breast cancer samples with equivocal human epidermal growth...
Introduction/ Background In situ hybridization (ISH) techniques, colorimetric (CISH) and fluorescenc...
Background: Identification of HER2 protein overexpression and/or amplification of the HER2 gene are ...
Human epidermal growth factor receptor 2 (HER2) has been evaluated in breast cancer patients to iden...
INTRODUCTION / BACKGROUND: In situ hybridization (ISH) techniques, colorimetric (CISH) and fluoresce...
The human epidermal growth factor receptor-2 (HER2) protein has been associated with breast cancer p...
HER2 amplification has been demonstrated in 15-25% of invasive breast carcinomas and can be assessed...
Aims: To compare visual and computerized image analysis of HER2 immunohistochemistry (IHC) with fluo...
HER2 assessment is routinely used to select patients with invasive breast cancer that might benefit ...
Aim Her2 protein is the key marker determining the choice of Herceptin therapy after a diagnosis of ...
Aims: The objective of this study was to evaluate the accuracy, ease of use and reproducibility of c...
Aims: To establish whether core needle biopsy (CNB) specimens processed with an accelerated processi...
Background: With the emerging role of digital imaging in pathology and the application of automated ...
Aim Whole slide images (WSIs) have stimulated a paradigm shift from conventional to digital patholog...
Background: The use of digital whole slide imaging for human epidermal growth factor receptor 2 (HER...
Background: Optimization of workflow for breast cancer samples with equivocal human epidermal growth...
Introduction/ Background In situ hybridization (ISH) techniques, colorimetric (CISH) and fluorescenc...
Background: Identification of HER2 protein overexpression and/or amplification of the HER2 gene are ...
Human epidermal growth factor receptor 2 (HER2) has been evaluated in breast cancer patients to iden...
INTRODUCTION / BACKGROUND: In situ hybridization (ISH) techniques, colorimetric (CISH) and fluoresce...
The human epidermal growth factor receptor-2 (HER2) protein has been associated with breast cancer p...
HER2 amplification has been demonstrated in 15-25% of invasive breast carcinomas and can be assessed...
Aims: To compare visual and computerized image analysis of HER2 immunohistochemistry (IHC) with fluo...
HER2 assessment is routinely used to select patients with invasive breast cancer that might benefit ...
Aim Her2 protein is the key marker determining the choice of Herceptin therapy after a diagnosis of ...
Aims: The objective of this study was to evaluate the accuracy, ease of use and reproducibility of c...
Aims: To establish whether core needle biopsy (CNB) specimens processed with an accelerated processi...
Background: With the emerging role of digital imaging in pathology and the application of automated ...