The 'cohort multiple Randomized Controlled Trial' design is an efficient and representative alternative to collect patient-reported outcomes and to evaluate experimental treatments in a routine care setting. It was implemented succesfully in a routine care rectal cancer setting and has resulted in satisfactory response rates to questionnaire and rates of patients randomized in trials. Since boost radiation can be used to increase the rate of pathological responses in rectal cancer patients undergoing chemoradiation, a new MRI-guided treatment was developed and is currently being evaluated using the cmRCT design in order to increase the percentage of patients that can proceed to organ-preserving treatment stratagies instead of radical surger...
PURPOSE: Dose-escalated chemoradiation (CRT) for locally advanced rectal cancer did not result in hi...
Patients with metastatic rectal cancer (mRC) have a poor prognosis and suffer from several symptoms ...
Colorectal cancer is the 3rd most common malignant disease worldwide and it represents the major pub...
The 'cohort multiple Randomized Controlled Trial' design is an efficient and representative alternat...
For most patients with rectal cancer, treatment consists of surgical resection of the rectum, which ...
Colorectal cancer is the third most common cancer in men and the second most common in women worldwi...
This thesis focuses on filling the knowledge gaps for an effective introduction of MRI-guided boost ...
Background/Aim: The aim of the study was to investigate boost volume definition, doses, and delivery...
Purpose: Pathologic complete tumor response after chemoradiation in patients with locally advanced r...
Colorectal cancer is one of the most common types of cancer. Staging of rectal cancer differs from c...
Purpose: Pathologic complete tumor response after chemoradiation in patients with locally advanced r...
Improvements in the treatment of rectal cancer patients have led to increased survival. Therefore, l...
BACKGROUND: Pre-operative chemoradiotherapy (CRT) for MRI-defined, locally advanced rectal cancer is...
Full list of author information is available at the end of the article(TRG 1). Secondary endpoints i...
Purpose: Dose-escalated chemoradiation (CRT) for locally advanced rectal cancer did not result in hi...
PURPOSE: Dose-escalated chemoradiation (CRT) for locally advanced rectal cancer did not result in hi...
Patients with metastatic rectal cancer (mRC) have a poor prognosis and suffer from several symptoms ...
Colorectal cancer is the 3rd most common malignant disease worldwide and it represents the major pub...
The 'cohort multiple Randomized Controlled Trial' design is an efficient and representative alternat...
For most patients with rectal cancer, treatment consists of surgical resection of the rectum, which ...
Colorectal cancer is the third most common cancer in men and the second most common in women worldwi...
This thesis focuses on filling the knowledge gaps for an effective introduction of MRI-guided boost ...
Background/Aim: The aim of the study was to investigate boost volume definition, doses, and delivery...
Purpose: Pathologic complete tumor response after chemoradiation in patients with locally advanced r...
Colorectal cancer is one of the most common types of cancer. Staging of rectal cancer differs from c...
Purpose: Pathologic complete tumor response after chemoradiation in patients with locally advanced r...
Improvements in the treatment of rectal cancer patients have led to increased survival. Therefore, l...
BACKGROUND: Pre-operative chemoradiotherapy (CRT) for MRI-defined, locally advanced rectal cancer is...
Full list of author information is available at the end of the article(TRG 1). Secondary endpoints i...
Purpose: Dose-escalated chemoradiation (CRT) for locally advanced rectal cancer did not result in hi...
PURPOSE: Dose-escalated chemoradiation (CRT) for locally advanced rectal cancer did not result in hi...
Patients with metastatic rectal cancer (mRC) have a poor prognosis and suffer from several symptoms ...
Colorectal cancer is the 3rd most common malignant disease worldwide and it represents the major pub...