Quantitative analysis of image metrics for reduced and standard dose pediatric 18F-FDG PET/MRI examinations
- Zucchetta, Pietro
- Branchini, Marco
- Zorz, Alessandra
- Bodanza, Valentina
- Cecchin, Diego
- Paiusco, Marta
- Bui, Franco
Publication date
January 2019
DOI Publisher
British Institute of Radiology ISSN
0007-1285Abstract
The study performs a comprehensive analysis of image metrics to objectively support the reduction of injected activity in pediatric oncology 18F-FDG PET/MR (18F-fludeoxyglucose PET/MR) examinations. Contrast-to-Noise Ratio (CNR), Normalized Noise (NN), tumor burden, and standardized uptake value (SUV) parameters stability were investigated to robustly define the acceptable reduced activity level that preserves the clinical utility of images, considering different PET applications
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