Introdução: O tratamento da Rinossinusite Crônica (RSC) tem sofrido poucos avanços nas últimas décadas. Uma das barreiras na aquisição de novas terapias é a falta de conhecimento pleno sobre sua fisiopatogenia. A carência de avanço decorre principalmente da complexa e provável multifatorialidade da RSC, associada à inexistência de um bom modelo animal que possa mimetizar os fenômenos biológicos que ocorrem em humanos. A maioria dos modelos animais de RSC descrita na literatura mimetiza uma infecção aguda ou promove bloqueio das vias de drenagem que, na maioria das vezes, não corresponde aos mecanismos encontrados nas RSC em humanos. Por outro lado, diversas evidências indicam que as bactérias exercem importante papel na fisiopatogenia da RS...
Background: Rabbits are useful for preclinical studies of sinusitis because of similar physiologic f...
PURPOSE: Evaluate and compare two different experimental techniques of maxillary sinus ostium occlus...
CONCLUSION: The results of our study suggest that Staphylococcus aureus enterotoxin A (SEA) may play...
Introdução: O tratamento da Rinossinusite Crônica (RSC) tem sofrido poucos avanços nas últimas décad...
Os modelos experimentais têm um papel importante no conhecimento dos mecanismos envolvidos na patogê...
Introduction: For decades, animals have been used in sinonasal experimental models, and the practice...
Experimental models for clinical studies of rhinosinusitis are needed. AIM: to define a reliable, so...
PURPOSE: Evaluate and compare two different experimental techniques of maxillary sinus ostium occlus...
SummaryExperimental models for clinical studies of rhinosinusitis are needed. Aim: to define a relia...
OBJECTIVE: The purpose of this study was to develop an experimental rhinosinusitis model by using ba...
Objective: The purpose of this study was to develop an experimental rhinosinusitis model by using ba...
BackgroundChronic rhinosinusitis (CRS) is a globally prevalent inflammatory condition of the paranas...
AbstractIntroductionIn order to better understand the pathophysiology of rhinosinusitis, several att...
Objectives/Hypothesis: The objectives were to determine the optimal sinusitis induction period and t...
Objectives/Hypothesis: The objectives were to determine the optimal sinusitis induction period and t...
Background: Rabbits are useful for preclinical studies of sinusitis because of similar physiologic f...
PURPOSE: Evaluate and compare two different experimental techniques of maxillary sinus ostium occlus...
CONCLUSION: The results of our study suggest that Staphylococcus aureus enterotoxin A (SEA) may play...
Introdução: O tratamento da Rinossinusite Crônica (RSC) tem sofrido poucos avanços nas últimas décad...
Os modelos experimentais têm um papel importante no conhecimento dos mecanismos envolvidos na patogê...
Introduction: For decades, animals have been used in sinonasal experimental models, and the practice...
Experimental models for clinical studies of rhinosinusitis are needed. AIM: to define a reliable, so...
PURPOSE: Evaluate and compare two different experimental techniques of maxillary sinus ostium occlus...
SummaryExperimental models for clinical studies of rhinosinusitis are needed. Aim: to define a relia...
OBJECTIVE: The purpose of this study was to develop an experimental rhinosinusitis model by using ba...
Objective: The purpose of this study was to develop an experimental rhinosinusitis model by using ba...
BackgroundChronic rhinosinusitis (CRS) is a globally prevalent inflammatory condition of the paranas...
AbstractIntroductionIn order to better understand the pathophysiology of rhinosinusitis, several att...
Objectives/Hypothesis: The objectives were to determine the optimal sinusitis induction period and t...
Objectives/Hypothesis: The objectives were to determine the optimal sinusitis induction period and t...
Background: Rabbits are useful for preclinical studies of sinusitis because of similar physiologic f...
PURPOSE: Evaluate and compare two different experimental techniques of maxillary sinus ostium occlus...
CONCLUSION: The results of our study suggest that Staphylococcus aureus enterotoxin A (SEA) may play...