[Excerpt] Dexamethasone-loaded carboxymethylchitosan/poly(amidoamine) dendrimer nanoparticles, CMC/PAMAM-Dex were successfully synthesized to find applications as a controlled system of relevant molecules in Bone Tissue Engineering. These are aimed at modulatingtheproliferation anddifferentiationofstem cells,both invitro and in vivo. In previous work, we have demonstrated that CMC/ PAMAM-Dex nanoparticles are internalized with high efficiency by different cell types, namely osteoblastic-cells, SaOs-2 and rat bone marrow stromal cells, RBMSCs. The biocompatibility of HA and SPCL scaffolds was also assessed by means of seeding RBMSCs onto the materials and performing a luminescent cell viability assay, after 24 and 72hrs. [...]info:eu-repo/sema...
To direct precursor cells toward the osteoblastic lineage, by using an intracellular nanocarrier rel...
Electrospun structures were proposed as scaffolds owing to their morphological and structural simila...
Introduction. Recently, polymeric nanoparticles (NPs) have attracted interest as delivery vehicles f...
There is an increasing interest in developing novel macromolecular vehicles for the intracellular an...
The control of stem cell differentiation to obtain osteoblasts in vivo is still regarded as a challe...
[Excerpt] Central nervous system associated disorders are a leading cause of disability worldwide. I...
[Excerpt] Growth and differentiation factors can be used to guide the biology in tissue engineering,...
Novel highly branched biodegradable macromolecular systems have been developed by grafting carboxyme...
Dendrimeric macromolecules are synthetic and spherical systems that have been attracting great deal...
This work aimed at studying the effects of dynamic culture conditions and biomimetic coating on bone...
[Excerpt] Fibrous structures mimicking the natural extracellular matrix (ECM) morphology are conside...
[Excerpt] Tissue engineering (TE) has emerged in the last decade of the 20th century as an alternati...
Disease, injury, and age problems compromise human quality of life and continuously motivate the sea...
Article first published online: 7 Oct. 2013Stem cells have received considerable attention by the sc...
[Excerpt] The aim of this study was to develop a bone tissue engineering scaffold with an inherent b...
To direct precursor cells toward the osteoblastic lineage, by using an intracellular nanocarrier rel...
Electrospun structures were proposed as scaffolds owing to their morphological and structural simila...
Introduction. Recently, polymeric nanoparticles (NPs) have attracted interest as delivery vehicles f...
There is an increasing interest in developing novel macromolecular vehicles for the intracellular an...
The control of stem cell differentiation to obtain osteoblasts in vivo is still regarded as a challe...
[Excerpt] Central nervous system associated disorders are a leading cause of disability worldwide. I...
[Excerpt] Growth and differentiation factors can be used to guide the biology in tissue engineering,...
Novel highly branched biodegradable macromolecular systems have been developed by grafting carboxyme...
Dendrimeric macromolecules are synthetic and spherical systems that have been attracting great deal...
This work aimed at studying the effects of dynamic culture conditions and biomimetic coating on bone...
[Excerpt] Fibrous structures mimicking the natural extracellular matrix (ECM) morphology are conside...
[Excerpt] Tissue engineering (TE) has emerged in the last decade of the 20th century as an alternati...
Disease, injury, and age problems compromise human quality of life and continuously motivate the sea...
Article first published online: 7 Oct. 2013Stem cells have received considerable attention by the sc...
[Excerpt] The aim of this study was to develop a bone tissue engineering scaffold with an inherent b...
To direct precursor cells toward the osteoblastic lineage, by using an intracellular nanocarrier rel...
Electrospun structures were proposed as scaffolds owing to their morphological and structural simila...
Introduction. Recently, polymeric nanoparticles (NPs) have attracted interest as delivery vehicles f...