Wheat protein synthesis elongation factor 1 was tested for binding to GTP analogs, including structures resembling "caps" that are present at the 5′-termini of most eukaryotic mRNAs. The interaction was assayed by determining the capacity of the analogs to inhibit the binding of [3H]GTP to elongation factor 1. Significant interaction of elongation factor 1 with G(5′)ppp(5′)G, G(5′)pppp(5′)G, and G(5′)ppp(5′)A was observed. Methylation of a ribose 2′-hydroxyl had very little effect, but methylation of the 7 position of guanosine greatly diminished the affinity of elongation factor 1 for these compounds. m7G(5′)ppp(5′)Cm, m7G(5′)ppp(5′)Um, and m7G(5′)ppp(5′)Am gave no detectable binding with EF1. © 1978
The exchange of flee guanine nucleotides with guanine nucleotides bound to elongation factor 2 (EF-2...
In all cells, ribosomes are inert in the absence of several proteins that promote each facet of prot...
AbstractTreatment of rat liver EF-2 with N-ethylmaleimide (MalNEt) did not affect the direct interac...
AbstractBinding of guanosine nucleotides to purified native and ADP-ribosylated wheat germ EF-2 was ...
AbstractThe structural specificity of the purified protein synthesis initiation factor 2 (eIF-2) fro...
As part of an attempt to understand the specific function and role of each subunit in multisubunit p...
Elongation factor G (EF-G) catalyses the translocation step in protein synthesis on the ribosome. Du...
AbstractElongation factors Tu and G (EF-Tu and EF-G) alternately interact with the ribosome during t...
Eukaryotic protein synthesis requires two protein factors which bind aminoacyl-tRNA in a GTP-depende...
Properties of heterogeneous forms of elongation factor (EF1) from cytoplasm of wheat embryos at diff...
The role of guanosine triphosphate (GTP) in the elongation factor Tu(EF-Tu)-promoted binding of amin...
The geometry of the Me2+. GTP complex at the active site of EF-Tu from Bacillus stearothermophilus h...
The properties and function of sulfhydryl groups in the polypeptide chain elongation factor G (EF-G)...
The interactions of elongation factor 1A (eEF1A) from Saccharomyces cerevisiae with elongation facto...
AbstractEukaryotic elongation factor 2 (EF-2) was shown to bind to F-actin as assayed by co-sediment...
The exchange of flee guanine nucleotides with guanine nucleotides bound to elongation factor 2 (EF-2...
In all cells, ribosomes are inert in the absence of several proteins that promote each facet of prot...
AbstractTreatment of rat liver EF-2 with N-ethylmaleimide (MalNEt) did not affect the direct interac...
AbstractBinding of guanosine nucleotides to purified native and ADP-ribosylated wheat germ EF-2 was ...
AbstractThe structural specificity of the purified protein synthesis initiation factor 2 (eIF-2) fro...
As part of an attempt to understand the specific function and role of each subunit in multisubunit p...
Elongation factor G (EF-G) catalyses the translocation step in protein synthesis on the ribosome. Du...
AbstractElongation factors Tu and G (EF-Tu and EF-G) alternately interact with the ribosome during t...
Eukaryotic protein synthesis requires two protein factors which bind aminoacyl-tRNA in a GTP-depende...
Properties of heterogeneous forms of elongation factor (EF1) from cytoplasm of wheat embryos at diff...
The role of guanosine triphosphate (GTP) in the elongation factor Tu(EF-Tu)-promoted binding of amin...
The geometry of the Me2+. GTP complex at the active site of EF-Tu from Bacillus stearothermophilus h...
The properties and function of sulfhydryl groups in the polypeptide chain elongation factor G (EF-G)...
The interactions of elongation factor 1A (eEF1A) from Saccharomyces cerevisiae with elongation facto...
AbstractEukaryotic elongation factor 2 (EF-2) was shown to bind to F-actin as assayed by co-sediment...
The exchange of flee guanine nucleotides with guanine nucleotides bound to elongation factor 2 (EF-2...
In all cells, ribosomes are inert in the absence of several proteins that promote each facet of prot...
AbstractTreatment of rat liver EF-2 with N-ethylmaleimide (MalNEt) did not affect the direct interac...